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遵循饮食指南与更好的身心健康质量相关:一项针对 728 名荷兰多发性硬化症患者的横断面调查结果。

Adherence to dietary guidelines is associated with better physical and mental quality of life: results from a cross-sectional survey among 728 Dutch MS patients.

机构信息

Division of Human Nutrition and Health, Wageningen University, Wageningen, Netherlands.

Department of Human Genetics, Radboud University Medical Center, Nijmegen, Netherlands.

出版信息

Nutr Neurosci. 2022 Aug;25(8):1633-1640. doi: 10.1080/1028415X.2021.1885240. Epub 2021 Feb 12.

Abstract

BACKGROUND

A healthy diet has been associated with less symptoms or progression of disease in multiple sclerosis (MS). However, whether specific diets are needed, or general healthy diet recommendations are sufficient is unknown.

OBJECTIVE

To investigate the association between diet quality, use of diets, and quality of life (QoL) in men and women with MS.

METHODS

Diet quality was measured with the Dutch Healthy Diet-index, which measures adherence to the Dutch Guidelines for a Healthy Diet. QoL was assessed with the MSQoL-54 questionnaire. A total of 728 people were included (623 women, 105 men). Multiple linear regression, stratified for gender, was used to analyse the data.

RESULTS

In women with MS, an association was found between diet quality and both physical and mental QoL after adjusting for several confounders (Physical Health Composite Score (=0.410; =0.001); Mental Health Composite Score (=0.462; =0.002)). Similar results were less pronounced in men. Subjects following a specific diet had higher diet quality and QoL than subjects not following a diet.

CONCLUSION

Adherence to the Dutch dietary guidelines is associated with better physical and mental QoL, especially in women. Following an MS-specific diet may help to adhere to these guidelines.

摘要

背景

健康的饮食与多发性硬化症(MS)患者的症状减轻或疾病进展减少有关。然而,目前尚不清楚是否需要特定的饮食,或者是否仅需要一般的健康饮食建议。

目的

调查饮食质量、饮食使用与多发性硬化症患者生活质量(QoL)之间的关系。

方法

采用荷兰健康饮食指数(Dutch Healthy Diet-index)来衡量饮食质量,该指数衡量了对荷兰健康饮食指南的依从性。使用 MSQoL-54 问卷评估 QoL。共纳入 728 人(623 名女性,105 名男性)。采用多元线性回归分析,按性别分层,分析数据。

结果

在女性多发性硬化症患者中,调整了几个混杂因素后,饮食质量与身体和心理 QoL 之间存在关联(身体健康综合评分(=0.410;=0.001);心理健康综合评分(=0.462;=0.002))。在男性中,结果则不那么明显。遵循特定饮食的受试者的饮食质量和 QoL 高于不遵循饮食的受试者。

结论

遵守荷兰饮食指南与更好的身体和心理 QoL 相关,尤其是在女性中。遵循多发性硬化症特定饮食可能有助于遵守这些指南。

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