中年过渡期、抑郁症及其临床管理。

The Midlife Transition, Depression, and Its Clinical Management.

机构信息

Department of Psychiatry, Queen's University School of Medicine, Providence Care Hospital, 752 King Street West, Kingston, Ontario K7L 4X3, Canada.

Department of Obstetrics and Gynecology, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4L8, Canada.

出版信息

Obstet Gynecol Clin North Am. 2021 Mar;48(1):215-229. doi: 10.1016/j.ogc.2020.11.009.

DOI:10.1016/j.ogc.2020.11.009

PMID:33573787

Abstract

The World Health Organization estimates that more than 260 million people are affected by depression worldwide, a condition that imposes a significant burden to individuals, their families, and society. Women seem to be disproportionately more affected by depression than men, and it is now clear that some women may experience windows of vulnerability for depression at certain reproductive stages across their life span, including the midlife transition. For some, age, the presence of cardiovascular or metabolic problems, and the emergence of significant, bothersome vasomotor symptoms and sleep problems may result in a compounded, deleterious impact on well-being and overall functioning.

摘要

世界卫生组织估计，全球有超过 2.6 亿人受到抑郁症的影响，这种疾病给个人、家庭和社会带来了巨大的负担。女性似乎比男性更容易受到抑郁症的影响，现在已经很清楚，一些女性在其整个生命周期中的某些生殖阶段可能会经历抑郁症的脆弱期，包括中年过渡期。对于一些人来说，年龄、心血管或代谢问题的存在，以及明显的、令人烦恼的血管舒缩症状和睡眠问题的出现，可能会对幸福感和整体功能产生叠加的、有害的影响。