Hashemipour Maryam Alsadat, Pooyafard Adeleh, Navabi Nader, Kakoie Shahla, Rahbanian Nazanin
DDS. MSc. Member of Kerman Social Determinants on Oral Health Research Center, Kerman University of Medical Sciences, Kerman, Iran, Professor of Oral Medicine, Department of Oral Medicine, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran.
Department of Oral Medicine, Dental School, Yazd University of Medical Sciences, Yazd, Iran.
J Educ Health Promot. 2020 Dec 29;9:358. doi: 10.4103/jehp.jehp_508_20. eCollection 2020.
The goal of treating cancer patients is to cure the patients and improve their quality of life (QoL) during their illness. The aim of this research was to assess the QoL in Iranian patients with head-and-neck cancer by European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35 (EORTC QLQ-H&N35) and University of Washington Quality of Life Questionnaire (UW-QoL).
In this cross-sectional study, Iranian variation of EORTC QLQ-H&N35 and UW-QoL questionnaires was administered to 210 patients with head-and-neck cancer. Patients who visited the Department of Oncology at Omid Hospital in Isfahan, Shafa Hospital in Kerman, and Emam Khomeini Hospital in Tehran were selected. Kruskal-Wallis test, general linear model multivariate of variance, multiple regression models, and SPSS version 21 were used for statistical analysis.
In the present research work, 210 patients with cancer in head and neck were under investigation, such that 128 patients (61%) were male and 82 patients (39%) were female. Only the patients with laryngeal cancer scored worse for dyspnea according to the scores from UW-QoL questionnaires. There were statistically significant differences for pain, swallowing, social eating, social contact, speech, taste/smell, and trismus based on the QLQ-H&N35. Lower QoL was observed in patients with advanced (Stage III + IV) tumors and treated with radiotherapy plus surgical method.
The study showed that quality of life differs due to location of tumor, stage of cancer, and treatment type.
治疗癌症患者的目标是治愈患者并在其患病期间提高他们的生活质量（QoL）。本研究的目的是通过欧洲癌症研究与治疗组织生活质量问卷-头颈部35（EORTC QLQ-H&N35）和华盛顿大学生活质量问卷（UW-QoL）评估伊朗头颈癌患者的生活质量。
在这项横断面研究中，将EORTC QLQ-H&N35和UW-QoL问卷的伊朗版本施用于210名头颈癌患者。选取了在伊斯法罕的奥米德医院、克尔曼的沙法医院和德黑兰的伊玛目霍梅尼医院肿瘤科就诊的患者。使用Kruskal-Wallis检验、一般线性模型多变量方差分析、多元回归模型以及SPSS 21版进行统计分析。
在本研究工作中，对210名头颈癌患者进行了调查，其中128名患者（61%）为男性，82名患者（39%）为女性。根据UW-QoL问卷的评分，只有喉癌患者在呼吸困难方面得分更差。基于QLQ-H&N35，在疼痛、吞咽、社交进食、社交接触、言语、味觉/嗅觉和牙关紧闭方面存在统计学显著差异。在晚期（III + IV期）肿瘤且接受放疗加手术治疗的患者中观察到较低的生活质量。
该研究表明，生活质量因肿瘤位置、癌症分期和治疗类型而异。
