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使用欧洲癌症研究与治疗组织问卷探讨印度西部头颈部癌症患者的生活质量。

Exploring quality of life among head-and-neck cancer patients in Western India using European organization for research and treatment of cancer questionnaires.

机构信息

Department of Public Health Dentistry, Siddhpur Dental College and Hospital, Patan, Gujarat, India.

Department of Community and Family Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

出版信息

J Cancer Res Ther. 2022 Jul-Sep;18(4):990-996. doi: 10.4103/jcrt.JCRT_450_20.

Abstract

BACKGROUND

Head-and-neck cancers (HNCs) are one of the major public health problems for both patients and the health-care providers in India. The clinical manifestations of HNC and its treatment can lead to negative effects on the quality of life (QoL) of the patient. The study is aimed to explore the QoL using the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaires among HNC patients in Western part of India.

MATERIALS AND METHODS

A cross-sectional prospective study was conducted among 400 HNC patients attending the tertiary cancer center. The QoL was assessed by using the EORTC core questionnaire (EORTC QLQ-C30) and EORTC head- and neck-specific questionnaire (EORTC QLQ-H and N35). The data were explored using means, standard deviation, medians, ranges, and proportions.

RESULTS

All the 400 patients had completed the questionnaire having a compliance rate of 100%. There was no missing data at the item level for the EORTC QLQ-C30 questionnaire. While the missing items for EORTC QLQ-H and N35 were: problems while swallowing food, problems with teeth, and sexuality. The mean functional score ranged from 74.22 to 93.49 for EORTC QLQ-C30. The mean symptoms score was found in the range from 3.25 to 81.50 for EORTC QLQ-H and N35.

CONCLUSION

Both questionnaires were comprehensive and well accepted by the patients. These questionnaires provided the information-related disease-specific QoL data, which otherwise is often missed. Health-care providers should not only focus on the clinical effects of treatment but also on QoL issues because it will improve overall patient care and survival.

摘要

背景

头颈部癌症(HNC)是印度患者和医疗保健提供者面临的主要公共卫生问题之一。HNC 的临床表现及其治疗可能会对患者的生活质量(QoL)产生负面影响。本研究旨在通过欧洲癌症研究与治疗组织(EORTC)生活质量问卷评估印度西部 HNC 患者的 QoL。

材料与方法

在一家三级癌症中心对 400 名 HNC 患者进行了横断面前瞻性研究。使用 EORTC 核心问卷(EORTC QLQ-C30)和 EORTC 头颈部专用问卷(EORTC QLQ-H 和 N35)评估 QoL。使用均值、标准差、中位数、范围和比例来探索数据。

结果

所有 400 名患者均完成了问卷,依从率为 100%。EORTC QLQ-C30 问卷没有项目缺失数据。而 EORTC QLQ-H 和 N35 的缺失项目为:吞咽食物困难、牙齿问题和性功能。EORTC QLQ-C30 的功能评分均值范围为 74.22 至 93.49。EORTC QLQ-H 和 N35 的症状评分均值范围为 3.25 至 81.50。

结论

两个问卷均全面且被患者广泛接受。这些问卷提供了与疾病特异性 QoL 相关的信息,否则通常会被遗漏。医疗保健提供者不仅应关注治疗的临床效果,还应关注 QoL 问题,因为这将改善整体患者护理和生存。

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