Zizolfi B, Foreste V, Di Spiezio Sardo A, Manzi A, Bifulco G, Carugno J
Department of Neuroscience Reproductive Sciences and Dentistry School of Medicine, University of Naples Federico II Naples, Italy.
Department of Public Health University of Naples Federico II Naples, Italy.
Facts Views Vis Obgyn. 2021 Jan 8;12(4):315-318.
Adenosarcoma is an extremely rare malignancy of the female genital tract composed of stromal sarcoma with a benign epithelial component. Current treatment recommendations include total hysterectomy with bilateral salpingo-oophorectomy, precluding future fertility. Although most frequently diagnosed in postmenopausal women, it is occasionally present in younger women of reproductive age with desire for future fertility. In 2015, we reported the case of a 23-year-old patient diagnosed with uterine adenosarcoma, who having strong desire of future fertility, opted for fertility sparing surgery. At a follow-up five years later, we can now report her case of spontaneous pregnancy and livebirth. A review of the literature concerning fertility outcomes in patients with uterine adenosarcoma undergoing fertility sparing therapeutic options is presented.
腺肉瘤是一种极其罕见的女性生殖道恶性肿瘤，由具有良性上皮成分的间质肉瘤组成。目前的治疗建议包括全子宫切除术加双侧输卵管卵巢切除术，这会排除未来的生育可能。虽然大多数病例在绝经后女性中诊断，但偶尔也会出现在有生育意愿的年轻育龄女性中。2015年，我们报告了一例23岁诊断为子宫腺肉瘤的患者，该患者强烈希望保留生育能力，选择了保留生育功能的手术。在五年后的随访中，我们现在可以报告她自然怀孕并分娩活婴的病例。本文对有关接受保留生育功能治疗方案的子宫腺肉瘤患者生育结局的文献进行了综述。
