CReATe Fertility Centre, 790 Bay Street, Suite 1100, Toronto, Ontario, M5G 1N8, Canada.
Faculty of Medicine, University of Toronto, Toronto, Canada.
J Assist Reprod Genet. 2021 Apr;38(4):907-916. doi: 10.1007/s10815-021-02103-6. Epub 2021 Feb 11.
This survey study aims to examine the quality of planned oocyte cryopreservation (POC) decision-making in the domains of decision change, decision difficulty, decision regret and informed choice.
Of the 224 women who completed at least one POC cycle between 2012 and 2018 at a Canadian academic IVF centre, 198 were reachable by email for anonymous survey participation.
Ninety-eight questionnaires were returned (response rate 49.5%). Of these, 86 fully completed questionnaires were analyzed for this study. Eighty-eight percent of respondents stated that it was a 'good decision' to cryopreserve oocytes, in retrospect. Despite this, 31% found the decision-making process to be 'difficult'. Three in five (61%) would have made 'exactly the same' decision without any change, yet slightly over a third (35%) would have made a 'similar' decision, but with option-related changes and process-related changes. A negative correlation between 'decision regret' and 'informed choice' was found (p < .005). Those who stated that they would have made exactly the 'same' POC decision were found to have a significantly higher 'informed choice' score compared to others who would have made a 'similar' or 'completely different' decision, in retrospect (p < .001). Respondents with lesser 'decision regret' were significantly more likely to appraise their decision as a well-informed choice (p < .001).
Our findings show that high-quality POC decision-making is accompanied by the perception of being able to make an informed choice, which can be achieved by providing patients with adequate information and individualized counselling to help patients set realistic expectations of cycle outcomes.
本调查研究旨在考察在决策改变、决策难度、决策后悔和知情选择等领域中，计划性卵母细胞冷冻保存（POC）决策的质量。
在 2012 年至 2018 年期间，在加拿大一家学术试管婴儿中心完成至少一个 POC 周期的 224 名女性中，有 198 名通过电子邮件可参与匿名调查。
有 98 份问卷被退回（回应率 49.5%）。其中，86 份完整的问卷被分析用于本研究。88%的受访者表示，回顾过去，冷冻保存卵母细胞是一个“好决定”。尽管如此，31%的人认为决策过程“困难”。五分之三（61%）的人会在没有任何改变的情况下做出“完全相同”的决定，但略超过三分之一（35%）的人会做出“类似”的决定，但会有选择相关的改变和过程相关的改变。“决策后悔”与“知情选择”呈负相关（p<.005）。发现那些表示他们会做出完全相同的 POC 决策的人，与那些表示会做出类似或完全不同的决策的人相比，他们的“知情选择”得分显著更高（p<.001）。后悔程度较低的受访者更有可能将其决策评估为明智的选择（p<.001）。
我们的研究结果表明，高质量的 POC 决策伴随着能够做出知情选择的感知，这可以通过向患者提供足够的信息和个性化咨询来实现，以帮助患者对周期结果设定现实的期望。
