Kostarczyk E, Fonberg E
Department of Neurophysiology, Nencki Institute of Experimental Biology, Warsaw, Poland.
Pavlov J Biol Sci. 1988 Jan-Mar;23(1):4-9. doi: 10.1007/BF02910538.
The effect of partial cortico-basomedial amygdaloid lesions on dogs' social behavior was investigated. The lesions did not affect the conditional instrumental responding (CRs) reinforced by petting or the dogs' need for petting (US). The lesions increased the number of intertrial responses (ITRs) in all dogs. Subsequently the effect of low amphetamine doses (0.5 mg/l kg) administered intramuscularly to the amygdalar animals on the same behavioral parameters of the social behavior was examined. Amphetamine did not affect CRs but dramatically increased the ITRs and dogs' need for petting. These findings suggest that the cortico-basomedial amygdaloid region may be involved in the cortical inhibitory mechanisms that are indispensable for promoting behavioral acts according to their usefulness and the situational context.
研究了犬类杏仁核皮质基底内侧部分损伤对其社会行为的影响。这些损伤并未影响由抚摸强化的条件性工具反应（CRs）或犬类对抚摸的需求（US）。损伤增加了所有犬类的试验间期反应（ITRs）数量。随后，研究了对杏仁核损伤的动物肌肉注射低剂量苯丙胺（0.5毫克/千克）对社会行为相同行为参数的影响。苯丙胺并未影响CRs，但显著增加了ITRs以及犬类对抚摸的需求。这些发现表明，杏仁核皮质基底内侧区域可能参与了皮质抑制机制，这些机制对于根据行为的有用性和情境来促进行为动作是不可或缺的。
