Lukaszewska I, Korczyński R, Markowska A, Kostarczyk E
Acta Neurobiol Exp (Wars). 1980;40(6):911-32.
Twelve rats with amygdaloid lesion (CBM group) and 20 sham operated (Control group) were tested. Emotional reactivity evaluated by six category scale showed transient decrease in CBM group with respect to Control one. The CBM lesion enhanced the locomotor activity in electromagnetic activity meter in the initial phase of confinement in the apparatus. Open-field ambulation was higher in CBM rats than in controls on the first day of examination, while on the second day both groups showed similar locomotor activity. No between group differences were found in response to introduction of novel object. Both groups preferred to stay in box placed in open-field than move around the field. However, CBM rats were engaged in box exploration, whereas controls spent major proportion of time sitting motionless. These results indicate that CBM lesion increases some components of response to novelty. The pattern of changes and their transitory character suggest that cortico-basomedial region of the amygdala is involved in the control of processes underlying the initial phase of responding to novel environment.
对12只杏仁核损伤大鼠（CBM组）和20只假手术大鼠（对照组）进行了测试。通过六分类量表评估的情绪反应性显示，CBM组相对于对照组有短暂下降。CBM损伤在将大鼠限制在实验装置中的初始阶段增强了其在电磁活动计中的运动活性。在检查的第一天，CBM大鼠在旷场中的走动比对照组更高，而在第二天两组显示出相似的运动活性。在引入新物体时未发现组间差异。两组都更愿意待在旷场中放置的盒子里而不是在场地周围走动。然而，CBM大鼠参与盒子探索，而对照组则将大部分时间用于静止坐着。这些结果表明，CBM损伤增加了对新奇事物反应的某些成分。变化模式及其短暂性表明，杏仁核的皮质基底内侧区域参与了对新环境反应初始阶段潜在过程的控制。
