Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, 420 Delaware Street SE, MMC 395, Minneapolis, MN, 55455, USA.
Masonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA.
Support Care Cancer. 2021 Oct;29(10):5663-5671. doi: 10.1007/s00520-021-06046-7. Epub 2021 Feb 12.
A cancer diagnosis and subsequent treatment can have a significant impact on an individual's quality of life. Differences in quality of life by sex among long-term melanoma survivors remain unclear. The objective of this study was to describe sex differences in cancer-specific psychosocial quality of life of long-term melanoma survivors.
Melanoma survivors 7-10 years post-diagnosis from a previously conducted population-based case-control study were recruited for a cross-sectional survey. Validated measures of psychosocial quality of life related to melanoma diagnosis were assessed. Outcomes were compared by sex using linear regression models adjusting for age, education, income, and marital status.
The survey response rate was 62% (433 females, 291 males; 86% stage I disease). Females were more likely to report changes in their appearance (p = 0.006) and being more fearful of recurrence (p = 0.001) or a second melanoma (p = 0.001) than males but were also more likely to report that melanoma had a positive impact on their lives (p < 0.0001). Males were more likely to agree with statements that emphasized that life's duration is limited (p < 0.0001).
Long-term melanoma survivors reported generally favorable measures of psychosocial quality of life related to their diagnosis. Females and males reported unique quality of life concerns and may require varied methods of support following a melanoma diagnosis.
癌症诊断和随后的治疗会对个人的生活质量产生重大影响。长期黑素瘤幸存者的性别之间生活质量的差异尚不清楚。本研究的目的是描述长期黑素瘤幸存者癌症特异性心理社会生活质量的性别差异。
从之前进行的一项基于人群的病例对照研究中招募了诊断后 7-10 年的黑素瘤幸存者,进行横断面调查。评估了与黑素瘤诊断相关的心理社会生活质量的验证性测量。使用线性回归模型比较了按性别调整年龄、教育、收入和婚姻状况后的结果。
调查的回复率为 62%(女性 433 名,男性 291 名;86%为 I 期疾病)。女性更有可能报告自己的外貌发生了变化(p=0.006),更担心复发(p=0.001)或再次患上黑素瘤(p=0.001),但也更有可能报告黑素瘤对他们的生活产生了积极的影响(p<0.0001)。男性更有可能同意强调生命期限有限的说法(p<0.0001)。
长期黑素瘤幸存者报告了与诊断相关的心理社会生活质量的一般有利措施。女性和男性报告了独特的生活质量问题,在诊断出黑素瘤后可能需要不同的支持方法。