Werner E B, Bishop K I, Koelle J, Douglas G R, LeBlanc R P, Mills R P, Schwartz B, Whalen W R, Wilensky J T
Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia 19104.
Arch Ophthalmol. 1988 May;106(5):619-23. doi: 10.1001/archopht.1988.01060130673024.
The visual fields of 30 patients (subjects) with glaucoma were sent to six experienced clinicians (observers). Each subject had at least four visual field examinations on the OCTOPUS 201 automated perimeter spanning at least one year. Each observer was asked to review the visual field data of each subject and determine whether the visual fields were stable, improved, or worse over time. The visual field data were then analyzed using six different statistical models. In only 15 of the 30 subjects did at least five of the six human observers agree on the behavior of the visual field. Agreement among the statistical models was better, with at least five of the six models agreeing on 22 of the 30 subjects. It was concluded that there is, at present, no validated technique for detecting progressive visual field loss in glaucoma using automated perimetry when relatively few visual fields are available for analysis.
30例青光眼患者（受试者）的视野检查结果被发送给6位经验丰富的临床医生（观察者）。每位受试者在OCTOPUS 201自动视野计上至少进行了4次视野检查，时间跨度至少为1年。要求每位观察者复查每位受试者的视野数据，并确定视野随时间推移是稳定、改善还是恶化。然后使用6种不同的统计模型对视野数据进行分析。在30例受试者中，只有15例的6位人类观察者中至少有5位对视野的变化情况达成一致。统计模型之间的一致性更好，6种模型中至少有5种在30例受试者中的22例上达成一致。得出的结论是，目前，当可供分析的视野相对较少时，使用自动视野计检测青光眼进展性视野缺损尚无经过验证的技术。
