Division of Cardiology, Weill Cornell Medicine-Qatar, Doha (I.Y.E.).
Heart and Vascular Institute, University of Pittsburgh Medical Center, PA (S.B., A.F.B.).
Circulation. 2021 Feb 16;143(7):727-738. doi: 10.1161/CIRCULATIONAHA.120.051460. Epub 2021 Feb 15.
Maternal mortality rates have been steadily increasing in the United States, and cardiovascular mortality is the leading cause of death among pregnant and postpartum women. Maternal stroke accounts for a significant burden of cardiovascular mortality. Data suggest that rates of maternal stroke have been increasing in recent years. Advancing maternal age at the time of birth and the increasing prevalence of traditional cardiovascular risk factors, and other risk factors, as well, such as hypertensive disorders of pregnancy, migraine, and infections, may contribute to increased rates of maternal stroke. In this article, we provide an overview of the epidemiology of maternal stroke, explore mechanisms that may explain increasing rates of stroke among pregnant women, and identify key knowledge gaps for future investigation in this area.
美国的孕产妇死亡率一直在稳步上升，心血管疾病死亡是导致孕妇和产后妇女死亡的主要原因。孕产妇脑卒中占心血管疾病死亡的很大一部分。数据表明，近年来孕产妇脑卒中的发生率一直在增加。产妇分娩时年龄的增长、传统心血管危险因素以及其他危险因素（如妊娠高血压疾病、偏头痛和感染）的流行，可能导致孕产妇脑卒中发生率的增加。本文概述了孕产妇脑卒中的流行病学，探讨了可能导致孕妇脑卒中发生率上升的机制，并确定了该领域未来研究的关键知识空白。
