Suppr超能文献

434例新冠肺炎医院死亡病例的多中心评估:大流行期间我们如何改善临终关怀?

Multicenter Evaluation of 434 Hospital Deaths From COVID-19: How Can We Improve End-of-Life Care During a Pandemic?

作者信息

Dewhurst Felicity, Billett Hannah, Simkiss Lauri, Bryan Charlotte, Barnsley Julie, Charles Max, Fleming Elizabeth, Grieve Jennifer, Hacking Sade, Howorth Kate, Huggin Amy, Kavanagh Emily, Kiltie Rachel, Lowery Lucy, Miller Dene, Nicholson Alex, Nicholson Lucy, Paxton Ann, Porteous Anna, Rowley Grace, Snell Kaly, Woods Elizabeth, Zabrocki Elizabeth, Frew Katherine, Srivastava Leena

机构信息

Newcastle University Population Health Sciences, Centre for Ageing and Vitality, Newcastle, Tyne and Wear, United Kingdom.

Northumbria Healthcare NHS Foundation Trust.

出版信息

J Pain Symptom Manage. 2021 May;61(5):e7-e12. doi: 10.1016/j.jpainsymman.2021.02.008. Epub 2021 Feb 13.

Abstract

CONTEXT

The pandemic has substantially increased the workload of hospital palliative care providers, requiring them to be responsive and innovative despite limited information on the specific end of life care needs of patients with COVID-19. Multi-site data detailing clinical characteristics of patient deaths from large populations, managed by specialist and generalist palliative care providers are lacking.

OBJECTIVES

To conduct a large multicenter study examining characteristics of COVID-19 hospital deaths and implications for care.

METHODS

A multi-center retrospective evaluation examined 434 COVID-19 deaths in 5 hospital trusts over the period March 23, 2020 to May 10, 2020.

RESULTS

Eighty three percent of patients were over 70%-32% were admitted from care homes. Diagnostic timing indicated over 90% of those who died contracted the virus in the community. Dying was recognized in over 90% of patients, with the possibility of dying being identified less than 48 hours from admission for a third. In over a quarter, death occurred less than 24 hours later. Patients who were recognized to be dying more than 72 hours prior to death are most likely to have access to medication for symptom control.

CONCLUSION

This large multicenter study comprehensively describes COVID-19 deaths throughout the hospital setting. Clinicians are alert to and diagnose dying appropriately in most patients. Outcomes could be improved by advance care planning to establish preferences, including whether hospital admission is desirable, and alongside this, support the prompt use of anticipatory subcutaneous medications and syringe drivers if needed. Finally, rapid discharges and direct hospice admissions could better utilize hospice beds and improve care.

摘要

背景

疫情大幅增加了医院姑息治疗提供者的工作量,要求他们在关于新冠病毒疾病(COVID-19)患者具体临终护理需求的信息有限的情况下做出响应并进行创新。目前缺乏由专科和全科姑息治疗提供者管理的、详细描述大量患者死亡临床特征的多地点数据。

目的

开展一项大型多中心研究,考察COVID-19患者在医院死亡的特征及其对护理的影响。

方法

一项多中心回顾性评估对2020年3月23日至2020年5月10日期间5家医院信托机构的434例COVID-19死亡病例进行了研究。

结果

83%的患者年龄超过70岁,32%的患者来自养老院。诊断时间表明,超过90%的死亡患者是在社区感染病毒的。超过90%的患者被确认处于临终状态,三分之一的患者在入院后不到48小时被确认可能死亡。超过四分之一的患者在24小时内死亡。在死亡前72小时以上被确认处于临终状态的患者最有可能获得控制症状的药物。

结论

这项大型多中心研究全面描述了整个医院环境中COVID-19患者的死亡情况。大多数患者的临床医生能够警觉并正确诊断临终状态。通过预先护理计划来确定患者的偏好,包括是否希望入院,以及在此基础上,在需要时支持及时使用预防性皮下用药和注射泵,可能会改善治疗结果。最后,快速出院和直接入住临终关怀机构可以更好地利用临终关怀床位并改善护理。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验