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理解创伤后精神病理学潜在维度的轨迹。

Understanding trajectories of underlying dimensions of posttraumatic psychopathology.

机构信息

Department of Psychology, University of California, Los Angeles (UCLA), Los Angeles, CA, United States.

Department of Medicine Statistics Core, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States.

出版信息

J Affect Disord. 2021 Apr 1;284:75-84. doi: 10.1016/j.jad.2021.01.086. Epub 2021 Feb 5.

Abstract

BACKGROUND

Research suggests four modal trajectories of psychological symptoms after traumatic injury: Resilient, Chronic, Delayed Onset, Recovery. However, most studies focus on symptoms of psychiatric disorders (e.g., posttraumatic stress disorder, depression), which are limited by heterogeneity and symptom overlap. We examined trajectories of cross-cutting posttraumatic symptom dimensions following traumatic injury and predictors of trajectory membership.

METHODS

In this longitudinal study of 427 predominantly Hispanic/Latino traumatic injury survivors, posttraumatic psychopathology symptoms were assessed during hospitalization and approximately one and five months post-trauma. Using latent class growth analysis, we estimated trajectories of several posttraumatic symptom dimensions: re-experiencing, avoidance, anxious arousal, numbing, dysphoric arousal, loss, and threat. We then examined sociodemographic and trauma-related characteristics (measured during hospitalization) as predictors of trajectory membership for each dimension.

RESULTS

Four trajectories (Resilient, Chronic, Delayed Onset, Recovery) emerged for all dimensions except loss and threat, which manifested three trajectories (Resilient, Chronic, Delayed Onset). Across dimensions, membership in the Chronic (vs. Resilient) trajectory was consistently predicted by unemployment (7 of 7 dimensions), followed by older age (3/7), female sex (3/7), and assaultive trauma (2/7). For several dimensions, unemployment also distinguished between participants who presented with similar symptom levels days after trauma, but then diverged over time.

LIMITATIONS

Measures of posttraumatic symptom dimension constructs differed across assessments.

CONCLUSIONS

This study provides evidence of distinct trajectories across transdiagnostic symptom dimensions after traumatic injury. Employment status emerged as the most important predictor of trajectory membership. Research is needed to better understand the etiologies and consequences of these posttraumatic symptom dimension trajectories.

摘要

背景

研究表明,创伤后心理症状存在四种模式轨迹:韧性、慢性、延迟发作、恢复。然而,大多数研究都集中在精神障碍症状上(例如,创伤后应激障碍、抑郁),这些研究受到异质性和症状重叠的限制。我们研究了创伤后交叉症状维度的轨迹以及轨迹成员的预测因素。

方法

在这项对 427 名主要为西班牙裔/拉丁裔创伤幸存者的纵向研究中,在住院期间和创伤后约一个月和五个月时评估创伤后精神病理学症状。使用潜在类别增长分析,我们估计了几种创伤后症状维度的轨迹:再体验、回避、焦虑觉醒、麻木、烦躁觉醒、丧失和威胁。然后,我们检查了社会人口统计学和与创伤相关的特征(在住院期间测量)作为每个维度轨迹成员身份的预测因素。

结果

除了丧失和威胁外,所有维度都出现了四个轨迹(韧性、慢性、延迟发作、恢复),而这两个维度表现出三个轨迹(韧性、慢性、延迟发作)。在所有维度中,慢性(与韧性)轨迹的成员身份始终由失业(7/7 个维度)预测,其次是年龄较大(3/7)、女性(3/7)和攻击性创伤(2/7)。对于几个维度,失业也区分了创伤后几天出现相似症状水平但随后随时间发散的参与者。

局限性

创伤后症状维度结构的测量在评估中有所不同。

结论

这项研究提供了创伤后跨诊断症状维度存在不同轨迹的证据。就业状况是轨迹成员身份的最重要预测因素。需要进一步研究以更好地了解这些创伤后症状维度轨迹的病因和后果。

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