• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

无框架立体定向脑活检:应用 RONNA G4 系统对 32 例患者行机器人辅助脑活检的前瞻性研究。

Frameless stereotactic brain biopsy: A prospective study on robot-assisted brain biopsies performed on 32 patients by using the RONNA G4 system.

机构信息

Department of Neurosurgery, University Hospital Dubrava, Zagreb, Croatia.

Faculty of Mechanical Engineering and Naval Architecture, University of Zagreb, Zagreb, Croatia.

出版信息

Int J Med Robot. 2021 Jun;17(3):e2245. doi: 10.1002/rcs.2245. Epub 2021 Mar 4.

DOI:10.1002/rcs.2245
PMID:33591608
Abstract

BACKGROUND

We present a novel robotic neuronavigation system (RONNA G4), used for precise preoperative planning and frameless neuronavigation, developed by a research group from the University of Zagreb and neurosurgeons from the University Hospital Dubrava, Zagreb, Croatia. The aim of study is to provide comprehensive error measurement analysis of the system used for the brain biopsy.

METHODS

Frameless stereotactic robot-assisted biopsies were performed on 32 consecutive patients. Post-operative CT and MRI scans were assessed to precisely measure and calculate target point error (TPE) and entry point error (EPE).

RESULTS

The application accuracy of the RONNA system for TPE was 1.95 ± 1.11 mm, while for EPE was 1.42 ± 0.74 mm. The total diagnostic yield was 96.87%. Linear regression showed statistical significance between the TPE and EPE, and the angle of the trajectory on the bone.

CONCLUSION

The RONNA G4 robotic system is a precise and highly accurate autonomous neurosurgical assistant for performing frameless brain biopsies.

摘要

背景

我们展示了一种新型的机器人神经导航系统(RONNA G4),由萨格勒布大学的一个研究小组和萨格勒布杜布拉瓦大学医院的神经外科医生开发,用于精确的术前规划和无框架神经导航。该研究的目的是提供用于脑活检的系统的全面误差测量分析。

方法

对 32 名连续患者进行了无框架立体定向机器人辅助活检。对术后 CT 和 MRI 扫描进行评估,以精确测量和计算靶点误差(TPE)和入点误差(EPE)。

结果

RONNA 系统的应用精度为 TPE 为 1.95±1.11mm,EPE 为 1.42±0.74mm。总的诊断率为 96.87%。线性回归显示 TPE 和 EPE 之间以及轨迹在骨头上的角度之间存在统计学意义。

结论

RONNA G4 机器人系统是一种精确和高度精确的自主神经外科助手,用于进行无框架脑活检。

相似文献

1
Frameless stereotactic brain biopsy: A prospective study on robot-assisted brain biopsies performed on 32 patients by using the RONNA G4 system.无框架立体定向脑活检:应用 RONNA G4 系统对 32 例患者行机器人辅助脑活检的前瞻性研究。
Int J Med Robot. 2021 Jun;17(3):e2245. doi: 10.1002/rcs.2245. Epub 2021 Mar 4.
2
Clinical application of the RONNA G4 system - preliminary validation of 23 robotic frameless brain biopsies.RONNA G4 系统的临床应用 - 23 例机器人无框架脑活检的初步验证。
Croat Med J. 2021 Aug 31;62(4):318-327. doi: 10.3325/cmj.2021.62.318.
3
Brain biopsy performed with the RONNA G3 system: a case study on using a novel robotic navigation device for stereotactic neurosurgery.使用RONNA G3系统进行脑活检:关于使用新型机器人导航设备进行立体定向神经外科手术的病例研究。
Int J Med Robot. 2018 Feb;14(1). doi: 10.1002/rcs.1884. Epub 2017 Dec 12.
4
Mobile intraoperative CT-assisted frameless stereotactic biopsies achieved single-millimeter trajectory accuracy for deep-seated brain lesions in a sample of 7 patients.在 7 例患者的样本中,移动术中 CT 辅助无框架立体定向活检实现了对深部脑病变的毫米级轨迹精度。
BMC Neurol. 2021 Jul 22;21(1):285. doi: 10.1186/s12883-021-02322-5.
5
Blurring the boundaries between frame-based and frameless stereotaxy: feasibility study for brain biopsies performed with the use of a head-mounted robot.模糊基于框架和无框架立体定向之间的界限:使用头戴式机器人进行脑活检的可行性研究。
J Neurosurg. 2015 Sep;123(3):737-42. doi: 10.3171/2014.12.JNS141781. Epub 2015 Jun 12.
6
Accuracy of robot-assisted versus optical frameless navigated stereoelectroencephalography electrode placement in children.儿童机器人辅助与光学无框架导航立体定向脑电图电极植入的准确性
J Neurosurg Pediatr. 2019 Mar 1;23(3):297-302. doi: 10.3171/2018.10.PEDS18227. Epub 2019 Jan 4.
7
Frameless Stereotactic Brain Biopsies: Comparison of Minimally Invasive Robot-Guided and Manual Arm-Based Technique.无框架立体定向脑活检:微创机器人引导技术与基于手动臂技术的比较。
Oper Neurosurg. 2020 Sep 1;19(3):292-301. doi: 10.1093/ons/opaa123.
8
Pushing the boundaries of accuracy and reliability during stereotactic procedures: A prospective study on 526 biopsies comparing the frameless robotic and Image-Guided Surgery systems.在立体定向手术中突破准确性和可靠性的界限:对无框架机器人和图像引导手术系统进行的 526 例活检的前瞻性研究。
J Clin Neurosci. 2022 Jan;95:203-212. doi: 10.1016/j.jocn.2021.11.034. Epub 2021 Dec 18.
9
Frameless stereotactic brain biopsy and external ventricular drainage placement using the RONNA G4 system.使用RONNA G4系统进行无框架立体定向脑活检和外置脑室引流管置入
J Surg Case Rep. 2022 May 31;2022(5):rjac151. doi: 10.1093/jscr/rjac151. eCollection 2022 May.
10
A comparison of the efficacy, safety, and duration of frame-based and Remebot robot-assisted frameless stereotactic biopsy.框架式和 Remebot 机器人辅助无框架立体定向活检的疗效、安全性和持续时间比较。
Br J Neurosurg. 2021 Jun;35(3):319-323. doi: 10.1080/02688697.2020.1812519. Epub 2020 Sep 17.

引用本文的文献

1
Triplanar Point Cloud Reconstruction of Head Skin Surface from Computed Tomography Images in Markerless Image-Guided Surgery.在无标记图像引导手术中基于计算机断层扫描图像对头皮肤表面进行三平面点云重建
Bioengineering (Basel). 2025 May 8;12(5):498. doi: 10.3390/bioengineering12050498.
2
Analysis of factors influencing diagnostic yield and target point error in robot-assisted stereotactic brain biopsy: a single-center experience.机器人辅助立体定向脑活检中影响诊断率和靶点误差的因素分析:单中心经验
Neurosurg Rev. 2025 Mar 24;48(1):317. doi: 10.1007/s10143-025-03463-8.
3
Launching Stealth AutoGuide robot for stereotactic biopsy procedures in a neurosurgical centre: learning curve and workflow optimization.
在神经外科中心推出用于立体定向活检程序的隐形自动引导机器人:学习曲线和工作流程优化
Front Robot AI. 2024 Dec 17;11:1437568. doi: 10.3389/frobt.2024.1437568. eCollection 2024.
4
Robot-assisted stereotactic brain biopsy: A systematic review and meta-analysis.机器人辅助立体定向脑活检:一项系统评价与荟萃分析。
Neurosurg Rev. 2024 Dec 4;47(1):886. doi: 10.1007/s10143-024-03122-4.
5
Clinical experiences and learning curves from robot-assisted neurosurgical biopsies with Stealth Autoguide™.使用Stealth Autoguide™进行机器人辅助神经外科活检的临床经验和学习曲线。
Neurooncol Adv. 2024 May 14;6(1):vdae079. doi: 10.1093/noajnl/vdae079. eCollection 2024 Jan-Dec.
6
Analysis of the Technical Accuracy of a Patient-Specific Stereotaxy Platform for Brain Biopsy.用于脑活检的患者特异性立体定向平台的技术准确性分析。
J Pers Med. 2024 Feb 5;14(2):180. doi: 10.3390/jpm14020180.
7
Preliminary clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma.多模态成像联合无框架机器人立体定向活检在原发性中枢神经系统淋巴瘤诊断中的初步临床应用
Heliyon. 2022 Dec 9;8(12):e12162. doi: 10.1016/j.heliyon.2022.e12162. eCollection 2022 Dec.
8
A Comparation Between Frame-Based and Robot-Assisted in Stereotactic Biopsy.基于框架与机器人辅助立体定向活检的比较
Front Neurol. 2022 Jul 18;13:928070. doi: 10.3389/fneur.2022.928070. eCollection 2022.
9
Frameless stereotactic brain biopsy and external ventricular drainage placement using the RONNA G4 system.使用RONNA G4系统进行无框架立体定向脑活检和外置脑室引流管置入
J Surg Case Rep. 2022 May 31;2022(5):rjac151. doi: 10.1093/jscr/rjac151. eCollection 2022 May.
10
A Bulk Retrospective Study of Robot-Assisted Stereotactic Biopsies of Intracranial Lesions Guided by Videometric Tracker.一项关于视频测量跟踪器引导下颅内病变机器人辅助立体定向活检的大规模回顾性研究。
Front Neurol. 2021 Aug 4;12:682733. doi: 10.3389/fneur.2021.682733. eCollection 2021.