Department of Chemical Engineering, Ege University, İzmir, 35100, Turkey.
Department of Bioengineering, Ege University, İzmir, 35100, Turkey.
Carbohydr Polym. 2021 Apr 15;258:117673. doi: 10.1016/j.carbpol.2021.117673. Epub 2021 Jan 22.
This study's primary purpose was to develop a new technique to stabilize high value-added bioactive volatile compounds present in essential oils to ensure their usability as chemical raw materials with enhanced stability. Selective isolation and encapsulation of various volatile compounds by changing the electrospraying process parameter, including voltage, flow rate, and β-Cyclodextrin concentration, were attributed to the formation of inclusion complexes between β-cyclodextrin and volatile compounds. Investigations regarding the effects of independent process variables on simultaneous isolation and selective encapsulation of volatile compounds during electrospraying of β-cyclodextrins were carried out mainly with TLC analyses. The TLC analyses were confirmed with GC, GC-MS, and H NMR analyses. It was possible to obtain nanoparticles with an average particle size between 25-160 nm with the designed system. Obtained data revealed that isolation and encapsulation of cumin aldehyde, camphene, isoborneol, and hexadecanoic acid, benzyl benzoate from labdanum essential oil were successfully achieved.
本研究的主要目的是开发一种新技术，以稳定存在于精油中的高附加值生物活性挥发性化合物，确保它们作为具有增强稳定性的化学原料的可用性。通过改变电喷雾工艺参数，包括电压、流速和β-环糊精浓度，对各种挥发性化合物进行选择性分离和包封，这归因于β-环糊精与挥发性化合物之间形成包合物。主要通过 TLC 分析研究了电喷雾过程中独立工艺变量对β-环糊精同时分离和选择性包封挥发性化合物的影响。TLC 分析得到了 GC、GC-MS 和 H NMR 分析的证实。使用设计的系统可以获得平均粒径在 25-160nm 之间的纳米粒子。获得的数据表明，成功地从劳丹脂精油中分离和包封了孜然醛、莰烯、异龙脑和十六烷酸、苯甲酸苄酯。
