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具有中空胆道系统的软肝体模。

Soft Liver Phantom with a Hollow Biliary System.

机构信息

Cyber Valley Research Group, Institute of Physical Chemistry, University of Stuttgart, Pfaffenwaldring 55, 70569, Stuttgart, Germany.

Department of General, Visceral and Transplant Surgery, University Hospital Tuebingen, 72072, Tuebingen, Germany.

出版信息

Ann Biomed Eng. 2021 Sep;49(9):2139-2149. doi: 10.1007/s10439-021-02726-x. Epub 2021 Feb 16.

DOI:10.1007/s10439-021-02726-x
PMID:33594636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8455397/
Abstract

Hepatobiliary interventions are regarded as difficult minimally-invasive procedures that require experience and skills of physicians. To facilitate the surgical training, we develop a soft, high-fidelity and durable liver phantom with detailed morphology. The phantom is anatomically accurate and feasible for the multi-modality medical imaging, including computer tomography (CT), ultrasound, and endoscopy. The CT results show that the phantom resembles the detailed anatomy of real livers including the biliary ducts, with a spatial root mean square error (RMSE) of 1.7 ± 0.7 mm and 0.9 ± 0.2 mm for the biliary duct and the liver outer shape, respectively. The sonographic signals and the endoscopic appearance highly mimic those of the real organ. An electric sensing system was developed for the real-time quantitative tracking of the transhepatic puncturing needle. The fabrication method herein is accurate and reproducible, and the needle tracking system offers a robust and general approach to evaluate the centesis outcome.

摘要

肝胆介入治疗被认为是具有挑战性的微创手术,需要医生具备经验和技能。为了便于手术培训,我们开发了一种具有详细形态的柔软、高保真和耐用的肝脏模型。该模型在解剖学上是准确的,适用于多种医学成像方式,包括计算机断层扫描(CT)、超声和内窥镜检查。CT 结果表明,该模型类似于真实肝脏的详细解剖结构,包括胆管,胆管和肝脏外轮廓的空间均方根误差(RMSE)分别为 1.7±0.7mm 和 0.9±0.2mm。超声信号和内窥镜外观高度模拟真实器官。为了实现经肝穿刺针的实时定量跟踪,开发了一种电感应系统。本文中的制造方法准确且可重复,并且该针跟踪系统提供了一种强大且通用的方法来评估穿刺结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/bbb55030bb77/10439_2021_2726_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/8c492df533c0/10439_2021_2726_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/2c48b7511f48/10439_2021_2726_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/6e62be9a55f3/10439_2021_2726_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/8b8bdc53b707/10439_2021_2726_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/cdfc862f9df0/10439_2021_2726_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/d76b68891928/10439_2021_2726_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/bbb55030bb77/10439_2021_2726_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/8c492df533c0/10439_2021_2726_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/2c48b7511f48/10439_2021_2726_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/6e62be9a55f3/10439_2021_2726_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/8b8bdc53b707/10439_2021_2726_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/cdfc862f9df0/10439_2021_2726_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/d76b68891928/10439_2021_2726_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723b/8455397/bbb55030bb77/10439_2021_2726_Fig7_HTML.jpg

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