Yang Yan, Zhou Zhongyin, Liu Rong, Chen Lu, Xiang Hongyu, Chen Na
Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China.
Department of Orthopaedic Surgery, Puren Hospital of Wuhan, Wuhan University of Science and Technology, Wuhan, Hubei 430060, P.R. China.
Exp Ther Med. 2018 Apr;15(4):3259-3264. doi: 10.3892/etm.2018.5831. Epub 2018 Feb 2.
Endoscopic retrograde cholangiopancreatography (ERCP) is an important treatment for inoperable hilar cholangiocarcinoma (HCC). The aim of the present study as to evaluate the clinical value of three-dimensional visualization (3DV) and 3D printing (3DP) technologies for ERCP in patients with HCC. The clinical data of 15 patients with HCC admitted for ERCP were analyzed retrospectively, including 9 males and 6 females. Thin-sliced data of computed tomography and magnetic resonance cholangiopancreatography (MRCP) were acquired and imported into Mimics Innovation Suite v17.0 software for 3D reconstruction. Standard Template Library files were exported for 3D printing. The target bile duct and Bismuth-Corlette (BC) classification were selected and performed respectively with the aid of Mimics Innovation Suite v17.0 software. The results were compared with the selected ones in ERCP. 3DV and 3DP models were successfully constructed for all patients, which presented the tumor, bile duct and the spatial relationship between them from multiple perspectives. The ERCP of all patients in the present study were performed successfully. The target bile duct screened by them had a high concordance rate of 86.7% with that in ERCP. The diagnostic accuracy of BC type results by 3DV and 3DP models was 93.3%. 3DV and 3DP technologies can accurately show the tumor and its associations with the surrounding bile duct, and it can be used to guide ERCP in HCC patients and improve the success rate of the operation.
内镜逆行胰胆管造影术（ERCP）是治疗无法手术切除的肝门部胆管癌（HCC）的重要方法。本研究旨在评估三维可视化（3DV）和3D打印（3DP）技术在HCC患者ERCP中的临床价值。回顾性分析15例因ERCP入院的HCC患者的临床资料，其中男性9例，女性6例。获取计算机断层扫描和磁共振胰胆管造影（MRCP）的薄层数据，并导入Mimics Innovation Suite v17.0软件进行三维重建。导出标准模板库文件进行3D打印。借助Mimics Innovation Suite v17.0软件分别选择并执行目标胆管和Bismuth-Corlette（BC）分类。将结果与ERCP中选定的结果进行比较。所有患者均成功构建了3DV和3DP模型，从多个角度呈现了肿瘤、胆管及其之间的空间关系。本研究中所有患者的ERCP均成功完成。他们筛选出的目标胆管与ERCP中的目标胆管的符合率高达86.7%。3DV和3DP模型对BC型结果的诊断准确率为93.3%。3DV和3DP技术可以准确显示肿瘤及其与周围胆管的关系，可用于指导HCC患者的ERCP并提高手术成功率。
