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使用沙罗拉纳/塞拉菌素外用溶液成功治疗一只猫的耳螨病。

Successful treatment of otodemodicosis due to with sarolaner/selamectin topical solution in a cat.

作者信息

Simpson Andrew C

机构信息

Dermatology Department, VCA Aurora Animal Hospital, Aurora, IL, USA.

出版信息

JFMS Open Rep. 2021 Jan 28;7(1):2055116920984386. doi: 10.1177/2055116920984386. eCollection 2021 Jan-Jun.

Abstract

CASE SUMMARY

A 10-year-old spayed female Russian Blue cat was presented with a 3-month history of excessive otic discharge and scratching, only involving the right ear. Other than a moderate amount of ceruminous exudate present within the right ear on video-otoscopic examination, there were no other cutaneous abnormalities. The cat was deemed to be otherwise in good health based on physical examination and several laboratory profiles. A diagnosis of otodemodicosis was determined due to the presence of a large number of mites retrieved from cerumen. Treatment consisted only of monthly topical application of sarolaner/selamectin to the nape of the neck with a marked reduction in mite counts and otic pruritus after a single dose. Complete resolution was achieved after a total of four doses.

RELEVANCE AND NOVEL INFORMATION

This is the first report to describe the resolution of mite infestation owing to after treatment with a sarolaner-containing spot-on product. In addition, to the best of the author's knowledge, this is the first report of any isoxazoline product used in the successful treatment of demodicosis affecting the ear canal. In general, there is a lack of reports describing safe and effective treatments for feline otodemodicosis. Topically applied sarolaner/selamectin resulted in resolution of mites while avoiding any potential ototoxic events from medications applied directly into the ear, and provided a treatment that was easier to apply than oral or injectable macrocyclic lactones.

摘要

病例摘要

一只10岁已绝育的雌性俄罗斯蓝猫,出现了3个月的耳部过多分泌物和抓挠症状,仅累及右耳。除了视频耳镜检查发现右耳内有适量的耵聍渗出物外,没有其他皮肤异常。根据体格检查和多项实验室检查结果,这只猫被认为其他方面健康状况良好。由于从耳垢中发现大量螨虫,诊断为耳螨病。治疗仅包括每月在颈部背侧局部应用沙罗拉纳/塞拉菌素,单次用药后螨虫数量和耳部瘙痒明显减少。总共四次用药后完全治愈。

相关性和新信息

这是第一份描述使用含沙罗拉纳的滴剂产品治疗后螨虫感染得到解决的报告。此外,据作者所知,这是首次报告使用任何异恶唑啉产品成功治疗影响耳道的蠕形螨病。总体而言,缺乏描述猫耳螨病安全有效治疗方法的报告。局部应用沙罗拉纳/塞拉菌素可使螨虫消失,同时避免了直接向耳内用药可能产生的任何潜在耳毒性事件,并且提供了一种比口服或注射大环内酯类药物更易于应用的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe8/7863163/0e802de00482/10.1177_2055116920984386-fig1.jpg

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