Division of Genetics, Department of Biology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY.
J Exp Med. 2021 Mar 1;218(3). doi: 10.1084/jem.20201753.
The identification of discrete subclasses within the immunoglobulin G (IgG) isotype by Grey and Kunkel (1964. J. Exp. Med.https://doi.org/10.1084/jem.120.2.253) provided the framework for our current understanding of differential IgG subclass activity in protective and self-reactive immune responses.
格雷和昆克尔(1964 年。实验医学杂志)的研究通过识别免疫球蛋白 G(IgG)同种型中的离散亚类,为我们目前对保护性和自身反应性免疫应答中不同 IgG 亚类活性的理解提供了框架。