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Emerging cell therapy for biliary diseases.

作者信息

Kurial Simone N T, Willenbring Holger

机构信息

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.

Department of Surgery, Division of Transplant Surgery, University of California San Francisco, San Francisco, CA, USA.

出版信息

Science. 2021 Feb 19;371(6531):786-787. doi: 10.1126/science.abg3179.

DOI:10.1126/science.abg3179
PMID:33602846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8549489/
Abstract
摘要

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Advanced therapies for congenital biliary tract malformation: From bench to bedside.先天性胆道畸形的先进疗法：从实验台到病床边
ILIVER. 2022 Aug 30;1(3):159-168. doi: 10.1016/j.iliver.2022.08.003. eCollection 2022 Sep.
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Modularized microrobot with lock-and-detachable modules for targeted cell delivery in bile duct.具有锁定和可拆卸模块的模块化微机器人，用于胆管中靶向细胞递药。
Sci Adv. 2023 Dec 15;9(50):eadj0883. doi: 10.1126/sciadv.adj0883.
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Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease.废弃供体肝脏中的人胆管上皮细胞可挽救胆道疾病小鼠模型中的胆管结构和功能。
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本文引用的文献

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Tissue-Engineered Bile Ducts for Disease Modeling and Therapy.用于疾病建模与治疗的组织工程胆管
Tissue Eng Part C Methods. 2021 Feb;27(2):59-76. doi: 10.1089/ten.TEC.2020.0283. Epub 2021 Feb 2.
2
Direct reprogramming of human umbilical vein- and peripheral blood-derived endothelial cells into hepatic progenitor cells.将人脐静脉和外周血来源的内皮细胞直接重编程为肝祖细胞。
Nat Commun. 2020 Oct 21;11(1):5292. doi: 10.1038/s41467-020-19041-z.
3
Clinical application of hepatocyte transplantation: current status, applicability, limitations, and future outlook.肝细胞移植的临床应用：现状、适用性、局限性和未来展望。
Expert Rev Gastroenterol Hepatol. 2020 Mar;14(3):185-196. doi: 10.1080/17474124.2020.1733975. Epub 2020 Mar 2.
4
Biliary Obstruction Promotes Multilineage Differentiation of Hepatic Stem Cells.胆管梗阻促进肝干细胞的多谱系分化。
Hepatol Commun. 2019 May 23;3(8):1137-1150. doi: 10.1002/hep4.1367. eCollection 2019 Aug.
5
Cholangiocyte pathobiology.胆管细胞病理生物学。
Nat Rev Gastroenterol Hepatol. 2019 May;16(5):269-281. doi: 10.1038/s41575-019-0125-y.
6
Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients.诱导多能干细胞的低免疫原性衍生物可逃避完全免疫活性同种异体受者的免疫排斥。
Nat Biotechnol. 2019 Mar;37(3):252-258. doi: 10.1038/s41587-019-0016-3. Epub 2019 Feb 18.
7
De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation.TGFβ 介导体肝细胞转分化形成新的胆道系统。
Nature. 2018 May;557(7704):247-251. doi: 10.1038/s41586-018-0075-5. Epub 2018 May 2.
8
Conversion of Terminally Committed Hepatocytes to Culturable Bipotent Progenitor Cells with Regenerative Capacity.终末分化的肝细胞向具有再生能力的可培养双能祖细胞的转化。
Cell Stem Cell. 2017 Jan 5;20(1):41-55. doi: 10.1016/j.stem.2016.10.007. Epub 2016 Nov 10.
9
Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes.人诱导多能干细胞来源胆管细胞的发育与特性研究
Lab Invest. 2015 Jun;95(6):684-96. doi: 10.1038/labinvest.2015.51. Epub 2015 Apr 13.
10
Bipotential adult liver progenitors are derived from chronically injured mature hepatocytes.双潜能成年肝脏祖细胞源自长期受损的成熟肝细胞。
Cell Stem Cell. 2014 Nov 6;15(5):605-18. doi: 10.1016/j.stem.2014.09.008. Epub 2014 Oct 9.