Cheng Tiantian, Fang Huijuan, Wang Yongchao, Wang Ying, Yang Zhishan, Wu Ruiying, Yang Dingquan
School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Department of Dermatology, China-Japan Friendship Hospital, Beijing, People's Republic of China.
Clin Cosmet Investig Dermatol. 2021 Feb 10;14:137-141. doi: 10.2147/CCID.S291170. eCollection 2021.
This study aimed to explore the relationship between serum ferritin levels and telogen effluvium.
A total of 193 telogen effluvium patients and 104 female androgenetic alopecia patients were included. We collected the test result of serum ferritin levels, compared with the results of 183 healthy subjects. Receiver Operator Characteristic curves were generated to assess the potential diagnostic value of serum ferritin in telogen effluvium patients.
The serum ferritin in telogen effluvium patients were significantly lower than that in the healthy control group (P = 0.000) or female androgenetic alopecia patients (P =0.000). Patients with lower serum ferritin levels got high odds to have telogen effluvium. The areas under the Receiver Operator Characteristic curve of serum ferritin levels were 0.735 and 0.645 for distinguishing telogen effluvium patients from healthy control subjects or female androgenetic alopecia patients.
Serum ferritin could be a potential biomarker for clinical diagnosis of telogen effluvium.
本研究旨在探讨血清铁蛋白水平与休止期脱发之间的关系。
共纳入193例休止期脱发患者和104例女性雄激素性脱发患者。我们收集了血清铁蛋白水平的检测结果，并与183名健康受试者的结果进行比较。绘制受试者工作特征曲线以评估血清铁蛋白在休止期脱发患者中的潜在诊断价值。
休止期脱发患者的血清铁蛋白显著低于健康对照组（P = 0.000）或女性雄激素性脱发患者（P = 0.000）。血清铁蛋白水平较低的患者发生休止期脱发的几率较高。血清铁蛋白水平的受试者工作特征曲线下面积在区分休止期脱发患者与健康对照受试者或女性雄激素性脱发患者时分别为0.735和0.645。
血清铁蛋白可能是休止期脱发临床诊断的潜在生物标志物。
