Frank Marcos G
Washington State University Spokane, Elson S. Floyd College of Medicine, Pharmaceutical and Biomedical Science Building 213, 412 E. Spokane Falls Blvd, Spokane, WA, 99202, USA.
Neurobiol Sleep Circadian Rhythms. 2021 Jan 25;10:100060. doi: 10.1016/j.nbscr.2021.100060. eCollection 2021 May.
In this commentary, I play the Devil's advocate and assume the title of High Contrarian. I intend to be provocative to challenge long-standing ideas about sleep. I blame all on Professor Craig Heller, who taught me to think this way as a graduate student in his laboratory. Scientists should fearlessly jump into the foaming edge of what we know, but also consider how safe are their intellectual harbors. There are many ideas we accept as 'known': that sleep is ubiquitous in the animal kingdom, that it serves vital functions, that it plays an essential role in brain plasticity. All of this could be wrong. As one example, I reexamine the idea that sleep is regulated by a mysterious 'homeostat' that determines sleep need based on prior wake time.
在这篇评论中，我唱唱反调，自封“超级反传统者”。我有意提出挑衅性观点，以挑战关于睡眠的长期观念。这一切都要怪克雷格·赫勒教授，我读研究生时在他的实验室，是他教会我这样思考。科学家应无畏地跳入我们已知领域的前沿，但也要考虑他们的知识港湾有多安全。有许多我们视为“已知”的观点：睡眠在动物界普遍存在，它发挥着至关重要的功能，它在大脑可塑性中起关键作用。而所有这些都可能是错的。例如，我重新审视了睡眠由一个神秘的“稳态调节器”调控这一观点，该调节器根据先前的清醒时间来确定睡眠需求。
