Büchner S A, Flückiger B, Rufli T
Dermatologische Universitätsklinik Basel.
Hautarzt. 1988 Feb;39(2):77-81.
Forms of lymphadenosis benigna cutis (Lbc) which run an unusual course may present considerable problems and are sometimes difficult to distinguish from malignant lymphomas of the skin on the basis of the clinical and histological picture. The case of a female patient is reported, who presented with plaque-like infiltrative lesions on both lower arms. The lesions were interpreted as being malignant lymphomas of the skin. After a progressive course of 6 years' duration, the diagnosis of an unusual plaque-like infiltrative form of Lbc caused by Borrelia was serologically confirmed by the demonstration of anti-Borrelia burgdorferi antibodies. Immunohistochemical examinations yielded the picture of a follicular pseudolymphoma with the formation of germ centres. After several weeks of penicillin therapy the skin lesions cleared completely.
良性皮肤淋巴组织增生症(Lbc)的不寻常病程形式可能会带来相当大的问题,有时根据临床和组织学表现难以与皮肤恶性淋巴瘤区分开来。本文报道了一名女性患者的病例,该患者双前臂出现斑块状浸润性病变。这些病变最初被诊断为皮肤恶性淋巴瘤。在经历了6年的进展期后,通过检测抗伯氏疏螺旋体抗体,血清学确诊为由伯氏疏螺旋体引起的不寻常斑块状浸润型Lbc。免疫组织化学检查显示为具有生发中心形成的滤泡性假淋巴瘤。经过数周的青霉素治疗,皮肤病变完全消退。