Emmanuel J C, Bassett M T, Smith H J
Blood Transfusion Service, Harare, Zimbabwe.
J Clin Pathol. 1988 Mar;41(3):334-6. doi: 10.1136/jcp.41.3.334.
To evaluate the addition of hepatitis vaccine to health schemes for hospital workers in Zimbabwe we undertook a cross sectional study of viral markers in 226 hospital workers and compared the results with 97 volunteer blood donor controls. One hundred and thirty one (58%) hospital workers had hepatitis markers compared with 45 (46%) of the donor group. Racial group was the strongest risk factor. Blacks were 70% more likely to have markers than whites. This racial difference was not explained by job status or patient contact. Our data suggest that work in a district general hospital does not constitute a clinically important hazard for hepatitis B infection. Because of the high cost of the vaccine, additional studies to assess the risk of hospital work in other settings in Zimbabwe are required before health policy regarding routine hepatitis B vaccination is determined.
为评估在津巴布韦医院工作人员的健康计划中添加肝炎疫苗的效果，我们对226名医院工作人员的病毒标志物进行了横断面研究，并将结果与97名志愿献血者对照进行比较。131名（58%）医院工作人员有肝炎标志物，而献血者组为45名（46%）。种族群体是最强的风险因素。黑人有标志物的可能性比白人高70%。这种种族差异无法用工作状态或与患者接触来解释。我们的数据表明，在地区综合医院工作对乙肝感染不构成临床上重要的风险。由于疫苗成本高昂，在确定关于常规乙肝疫苗接种的卫生政策之前，需要进行更多研究以评估津巴布韦其他环境中医院工作的风险。
