Department of Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital, No.123, Ta-Pei Road, Niao-Song District, Kaohsiung, 833, Taiwan.
Department of General Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
BMC Surg. 2021 Feb 21;21(1):94. doi: 10.1186/s12893-021-01108-3.
During clinical practice we have noticed that some patients with hyperthyroidism have finer skin with less wrinkles, pores, and spots after thyroidectomy, and the improvement can be observed within a few weeks after the operation. However, there is no evidence or study in the literature to proof this finding.
This study was designed to evaluate and quantify the skin characters of patients with hyperthyroidism before and after thyroidectomy.
This is a prospective study to include patients with hyperthyroidism who received total thyroidectomy between March 1st, 2018 and February 28th, 2019. The patients received blood test for T4 and TSH analysis and VISIA measurements for skin texture quantification, at the preoperative stage, three, and six months postoperatively. A total of 8 patients were included. Repeated measurement was used to determine the lab data and VISIA measurement changes before and after the operation. Mauchly's sphericity test was performed to determine whether the violation of sphericity occurs, and the Greenhouse-Geisser correction was used when the violation of sphericity occurs.
All the patients were female and generally healthy without systemic medical disease except the hyperthyroidism. The T4 and TSH levels were not significantly different before and after the thyroidectomy. In terms of the skin character measurements, the wrinkles, texture, pores, UV spots, and brown spots were not improved after thyroidectomy. A trend of improvement in spots, red area, and porphyrin was noted, although not statistically significant.
Surgical removal of the thyroid gland in patients with hyperthyroidism does not improve the skin quality and texture in examinations via the VISIA system.
在临床实践中，我们注意到一些甲状腺功能亢进症患者在甲状腺切除术后皮肤变得更加细腻，皱纹、毛孔和斑点减少，这种改善可以在手术后几周内观察到。然而，文献中没有证据或研究证明这一发现。
本研究旨在评估和量化甲状腺功能亢进症患者甲状腺切除术前和术后的皮肤特征。
这是一项前瞻性研究，纳入 2018 年 3 月 1 日至 2019 年 2 月 28 日期间接受甲状腺全切除术的甲状腺功能亢进症患者。患者在术前、术后 3 个月和 6 个月接受 T4 和 TSH 分析的血液检查和 VISIA 皮肤纹理定量测量。共纳入 8 例患者。采用重复测量法确定手术前后实验室数据和 VISIA 测量的变化。采用 Mauchly 球形检验确定是否发生球形度违反，当发生球形度违反时采用 Greenhouse-Geisser 校正。
所有患者均为女性，一般健康，除甲状腺功能亢进症外无系统性疾病。甲状腺切除术后 T4 和 TSH 水平无显著差异。在皮肤特征测量方面，皱纹、纹理、毛孔、UV 斑点和棕色斑点在甲状腺切除术后没有改善。尽管没有统计学意义，但注意到斑点、红斑区和卟啉的改善趋势。
甲状腺功能亢进症患者甲状腺切除手术不能通过 VISIA 系统改善皮肤质量和纹理。
