Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Department of Parasitology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Trop Biomed. 2020 Jun 1;37(2):318-323.
Domestic mites have been recognized as the most common allergen responsible for respiratory allergy. Herein, we report a case of anaphylaxis due to ingestion of dust mitecontaminated food. A 14-year-old boy presented to the Emergency Department with chest discomfort, wheezing, eyelid angioedema, and urticarial rash twice in a month after eating meals, including tempura fried squids and onion fritters (containing wheat flour, eggs, squid, and onion). Anaphylaxis had been diagnosed and successfully treated. The investigations showed that the patient was sensitive to house dust mites. Positive skin prick-to-prick test response to incriminated flour and negative tests to wheat allergen extract and uncontaminated flour were demonstrated. The microscopic analysis of causative cooking flour identified the presence of Dermatophagoides farinae. During the oral food challenge test, the patient was able to eat tempura-fried squids and onion fritters, made with uncontaminated flour, without any adverse reaction. Hence, oral ingestion of dust mite-contaminated food was the culprit of this severe allergic reaction.
国内尘螨已被认为是引起呼吸道过敏的最常见过敏原。在此，我们报告一例因食用受尘螨污染食物引起的过敏反应。一名 14 岁男孩因食用包括天妇罗炸鱿鱼和洋葱饼（含面粉、鸡蛋、鱿鱼和洋葱）在内的食物后，一个月内两次出现胸部不适、喘息、眼睑血管性水肿和荨麻疹，到急诊科就诊。已诊断为过敏反应，并成功治疗。调查显示，患者对屋尘螨敏感。对可疑面粉进行皮内点刺试验呈阳性反应，而对小麦过敏原提取物和未受污染面粉的检测结果为阴性。对致病烹饪面粉的显微镜分析确定存在粉尘螨。在口服食物激发试验中，患者能够食用未受污染面粉制作的天妇罗炸鱿鱼和洋葱饼，无任何不良反应。因此，口服摄入受尘螨污染的食物是导致此次严重过敏反应的罪魁祸首。
