de Koning P, Wieneke G H, van der Most van Spijk D, van Huffelen A C, Gispen W H, Jennekens F G
Division of Molecular Neurobiology, Rudolf Magnus Institute for Pharmacology, Utrecht, The Netherlands.
J Neurol Neurosurg Psychiatry. 1988 Mar;51(3):403-11. doi: 10.1136/jnnp.51.3.403.
The technique of the macro-EMG was used to estimate the number of motor units in the tibialis anterior muscles of healthy subjects in a wide range of ages, and of patients with myasthenia gravis and patients with amyotrophic lateral sclerosis or spinal muscular atrophy. The results obtained suggest a decrease in the number of motor units in the tibialis anterior muscle with increasing age in normal subjects. In myasthenic patients the motor unit count was within the normal range for their age group. Patients with motor neuron disorders on the average had a very low number of motor units.
采用宏肌电图技术对不同年龄段的健康受试者、重症肌无力患者以及肌萎缩侧索硬化症或脊髓性肌萎缩症患者的胫前肌运动单位数量进行评估。所得结果表明,正常受试者胫前肌的运动单位数量随年龄增长而减少。重症肌无力患者的运动单位计数在其年龄组的正常范围内。运动神经元疾病患者的运动单位数量平均非常低。