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一种估计肌肉中运动单位数量的新方法。I. 对照受试者和重症肌无力患者。

A new method for the estimation of the number of motor units in a muscle. I. Control subjects and patients with myasthenia gravis.

作者信息

Ballantyne J P, Hansen S

出版信息

J Neurol Neurosurg Psychiatry. 1974 Aug;37(8):907-15. doi: 10.1136/jnnp.37.8.907.

Abstract

A new method, incorporating on-line computer analysis, is described for the estimation of the numbers of motor units in human muscle. The results obtained in the extensor digitorum brevis muscle in normal subjects and patients with myasthenia gravis are presented. These indicate that the numbers of motor units in that muscle in patients with myasthenia gravis are within the normal range, in contrast with the reduction in numbers reported by other workers using a different technique. Evidence is presented to suggest that the discrepancy in these results is due to increased sensitivity and discrimination of the computerized method. Several hypotheses on the aetiology of a number of neuromuscular diseases, based on the results of the other method, may require reevaluation.

摘要

本文描述了一种结合在线计算机分析的新方法,用于估计人体肌肉中的运动单位数量。文中展示了在正常受试者和重症肌无力患者的趾短伸肌中获得的结果。这些结果表明,重症肌无力患者该肌肉中的运动单位数量在正常范围内,这与其他研究人员使用不同技术报告的数量减少情况形成对比。有证据表明,这些结果的差异是由于计算机化方法的敏感性和辨别力提高所致。基于其他方法的结果对一些神经肌肉疾病病因提出的几种假设可能需要重新评估。

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