Parker William D, Jones Keith
Head and Neck Unit, Royal Derby Hospital, Derby, UK.
J Surg Case Rep. 2021 Feb 15;2021(2):rjaa557. doi: 10.1093/jscr/rjaa557. eCollection 2021 Feb.
We would like to describe a case of Burkitt's lymphoma in a 37-year-old lady, who initially presented to her General Dental Practitioner (GDP) complaining of pain and episodic numbness in the right lip and chin. The initial diagnosis was irreversible pulpitis of the lower right second molar (LR7) and despite having an extraction of the affected tooth her problems persisted. The patient also developed pain in the spine and limbs, accompanied by lethargy and weakness. After seeing multiple different practitioners, she was referred to her local Oral and Maxillofacial Surgery department. Cross-sectional imaging was requested and demonstrated disseminated malignancy. Histology following open trans-oral biopsy revealed a diagnosis of Burkitt's lymphoma prompting an urgent haematology referral, and she successfully completed a chemotherapy regimen. This case highlights the importance of a thorough diagnostic process in the presence of persistent and/or atypical symptoms.
我们想描述一例37岁女性的伯基特淋巴瘤病例,该患者最初因右侧嘴唇和下巴疼痛及间歇性麻木前往其普通牙科医生(GDP)处就诊。初步诊断为右下第二磨牙(LR7)不可逆性牙髓炎,尽管拔除了患牙,她的问题仍持续存在。患者还出现了脊柱和四肢疼痛,并伴有嗜睡和虚弱。在看过多个不同科室的医生后,她被转诊至当地口腔颌面外科。进行了横断面成像检查,显示为播散性恶性肿瘤。经口开放活检后的组织学检查显示诊断为伯基特淋巴瘤,促使紧急转诊至血液科,她成功完成了化疗方案。该病例突出了在存在持续和/或非典型症状时进行全面诊断过程的重要性。