手性在大麻素研究中的作用。
Chirality in Cannabinoid Research.
机构信息
PerkinElmer Health Sciences, Inc., Waltham, Massachusetts, USA.
出版信息
Cannabis Cannabinoid Res. 2021 Feb 12;6(1):1-4. doi: 10.1089/can.2020.0027. eCollection 2021.
Abstract
Mankind has long utilized for diverse purposes. However, it has only been since the late 19th century that its individual cannabinoids began to be isolated, analyzed, and synthesized. By the mid-20th century it was discovered that many cannabinoids were asymmetric, with chirality often controlling their pharmacology. Increasingly accurate measurement and understanding of cannabinoid chirality will facilitate their synthesis and accelerate their medicinal applications.
摘要
人类长期以来一直将大麻用于各种用途。然而，直到 19 世纪后期，大麻的各种单一成分才开始被分离、分析和合成。到了 20 世纪中叶，人们发现许多大麻素都是不对称的，手性往往控制着它们的药理学。对大麻素手性的日益精确的测量和理解将有助于它们的合成，并加速它们的药用应用。
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