Gupta Varsha, Sharma Shiwani, Pal Kritika, Goyal Poonam, Agarwal Deepak, Chander Jagdish
Department of Microbiology, Government Medical College Hospital, Chandigarh,India.
Department of Obstetrics & Gynecology , Government Medical College Hospital, Chandigarh,India.
Infect Disord Drug Targets. 2021;21(7):e300821191666. doi: 10.2174/1871526521666210222125215.
Serratia spp. is a common enteric bacterium generally thought not to be pathogenic in the gastrointestinal tract. Serratia marcescens is a member of the genus Serratia, which is a part of the family Enterobacteriales. Of all Serratia species, S. marcescens is the most common clinical isolate and the most important human pathogen.
We discuss here four cases of Serratia marcescens which were reported in our laboratory at the Department of Microbiology Government Medical College and Hospital Chandigarh within six months of duration.
All the samples were processed and identified using standard microbiological techniques. The isolates of Serratia marcescens were identified, depending upon their biochemical and morphological characteristics, and further confirmed by MALDI-TOF-MS, PGIMER Chandigarh.
In one of the four cases, polymicrobial infection was observed, and among the cases, one patient was diabetic and the rest three patients were immunocompetent. The importance of detection of Serratia marcescens is related to the concern regarding its increased spread in hospital settings as nosocomial infection.
We need to identify and isolate this pathogen not thinking of it only as a contaminant and opportunistic pathogen but as a pathogen which can lead to serious infections in hospital settings.
沙雷氏菌属是一种常见的肠道细菌，一般认为在胃肠道中不具有致病性。粘质沙雷氏菌是沙雷氏菌属的成员，属于肠杆菌科。在所有沙雷氏菌属物种中，粘质沙雷氏菌是最常见的临床分离株，也是最重要的人类病原体。
本文讨论了在昌迪加尔政府医学院和医院微生物科我们实验室六个月内报告的四例粘质沙雷氏菌病例。
所有样本均采用标准微生物技术进行处理和鉴定。根据其生化和形态学特征对粘质沙雷氏菌分离株进行鉴定，并由昌迪加尔PGIMER通过基质辅助激光解吸电离飞行时间质谱进一步确认。
在四例病例中，有一例观察到混合感染，病例中，一名患者患有糖尿病，其余三名患者免疫功能正常。检测粘质沙雷氏菌的重要性与对其在医院环境中作为医院感染传播增加的担忧有关。
我们需要识别和分离这种病原体，不要仅仅将其视为污染物和机会性病原体，而应将其视为一种可在医院环境中导致严重感染的病原体。
