Hoffschir F, Prieur M, Dutrillaux B
Commissariat à l'Energie Atomique, IPSN/DPR/SPS/LGE, Fontenay-aux-Roses, France.
Mutat Res. 1988 May;199(1):103-10. doi: 10.1016/0027-5107(88)90235-7.
In order to study the induction of rearrangements by gamma-rays in relation to chromosomal size and morphology, experiments were conducted in an Ateles, a species with a rather unusual karyotype among primates. It possesses some very large chromosomes, which tend to be too rarely affected, especially by intrachanges like inversions. Both their large size and their characteristic banding pattern suggest that this low involvement is not due to difficulty of analysis. This suggests very strongly that chromosomal involvement in rearrangements is not a function of size. The possible role of other factors involved in chromosomal rearrangements like chromosome position during interphase are discussed.
为了研究γ射线诱导的重排与染色体大小和形态的关系，在蛛猴属进行了实验，蛛猴属在灵长类中具有相当不寻常的核型。它拥有一些非常大的染色体，这些染色体往往很少受到影响，尤其是像倒位这样的内部变化。它们的大尺寸和特征性的带型表明，这种低参与度并非由于分析困难。这强烈表明，染色体参与重排不是大小的函数。还讨论了其他参与染色体重排的因素的可能作用，如间期染色体位置。
