Shen Youjin, Qi Xiaokun, Wan Tingyu
Southern Medical University, Guangzhou City, Guangdong Province, Beijing, China.
Department of Neurology, The Sixth Medical Center of PLA of China General Hospital, Beijing, China.
Ann Indian Acad Neurol. 2020 Sep-Oct;23(5):602-607. doi: 10.4103/aian.AIAN_591_19. Epub 2020 Feb 11.
Vestibular migraine (VM) is one of the most debilitating chronic diseases that is currently underdiagnosed and undertreated. The treatment of VM is a dynamic and rapidly advancing area of research. New developments in this field have the potential to improve the diagnosis and provide more individualized treatments for this condition. In this review, we discussed the progress of evidence-based treatment of VM, including pharmacotherapy and nonmedical methods. A search of the literature was conducted up to September 2019. In order to control or cure VM, patients should follow three steps. First, patients should comply with diet and behavioral medication; Second, during the attack of VM, patients should take medicine to control the symptoms. These acute attack treatment of VM consists of antiemetic medications (e.g., dimenhydrinate and benzodiazepines), anti-vertigo medicine, and analgesics (e.g. triptans). Third, prophylactic medicine (e.g., propranolol, topiramate, valproic aid, lamotrigine, and flunarizine) can be used to reduce the frequency and severity of VM attack. Also, vestibular rehabilitation (VR) treatment should be considered for all VM. Meanwhile, we also propose to establish a culture of prevention which is essential for reducing the personal, social and economic burden of VM.
前庭性偏头痛(VM)是目前诊断不足且治疗不充分的最使人衰弱的慢性疾病之一。VM的治疗是一个动态且快速发展的研究领域。该领域的新进展有可能改善诊断并为这种疾病提供更个性化的治疗方法。在本综述中,我们讨论了VM循证治疗的进展,包括药物治疗和非药物方法。截至2019年9月进行了文献检索。为了控制或治愈VM,患者应遵循三个步骤。首先,患者应遵守饮食和行为调节;其次,在VM发作期间,患者应服药以控制症状。这些VM急性发作的治疗包括止吐药物(如茶苯海明和苯二氮䓬类药物)、抗眩晕药物和镇痛药(如曲坦类药物)。第三,预防性药物(如普萘洛尔、托吡酯、丙戊酸、拉莫三嗪和氟桂利嗪)可用于降低VM发作的频率和严重程度。此外,所有VM患者均应考虑进行前庭康复(VR)治疗。同时,我们还建议建立预防文化,这对于减轻VM的个人、社会和经济负担至关重要。