老年人骨质疏松症和肌肉减少症的预防。

The prevention of osteoporosis and sarcopenia in older adults.

机构信息

Department of Family Medicine, UConn Health, Farmington, Connecticut, USA.

Center on Aging, UConn Health, Farmington, Connecticut, USA.

出版信息

J Am Geriatr Soc. 2021 May;69(5):1388-1398. doi: 10.1111/jgs.17043. Epub 2021 Feb 23.

Abstract

Osteoporosis and sarcopenia are common in older adults. Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. Bone fractures can result in changes in posture, pain, the need for surgical repair and functional impairment. Sarcopenia is the progressive and generalized loss of skeletal muscle mass, strength and/or physical performance. Older adults with sarcopenia experience increased risk of frailty, disability, hospitalizations, mortality, and a reduced quality of life. In this narrative review we provide guidance regarding the prevention of both osteoporosis and sarcopenia, including interventions that prevent both conditions from occurring, recommended screening and treatment to prevent progression.

摘要

骨质疏松症和肌肉减少症在老年人中很常见。骨质疏松症是一种全身性骨骼疾病,其特征是骨量低和骨组织微观结构恶化,导致骨脆性增加和骨折易感性增加。骨折会导致姿势改变、疼痛、需要手术修复和功能障碍。肌肉减少症是一种进行性和全身性的骨骼肌量、力量和/或身体机能丧失。患有肌肉减少症的老年人更容易出现虚弱、残疾、住院、死亡以及生活质量降低。在这篇叙述性综述中,我们提供了关于预防骨质疏松症和肌肉减少症的指导,包括预防这两种疾病发生的干预措施、建议的筛查和治疗以防止疾病进展。

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