Lotfi Hadi, Sankian Mojtaba, Meshkat Zahra, Khalifeh Soltani Ahmad, Aryan Ehsan
Antimicrobial Resistance Research Center Mashhad University of Medical Sciences Mashhad Iran.
Laboratory of Microbiology, Department of Medical Microbiology Ghaem University Hospital, Mashhad University of Medical Sciences Mashhad Iran.
Respirol Case Rep. 2021 Feb 22;9(3):e00719. doi: 10.1002/rcr2.719. eCollection 2021 Mar.
Incidence of pulmonary infection is increasing and diagnosis and treatment are challenging. We surveyed the clinical features, risk factors, diagnosis, and management in 20 patients from northeastern Iran diagnosed by line probe assay and confirmed by sequencing the () region and carried out a literature review using the keywords "pulmonary infection" and "." The mean age of patients was 55.1 years, with 80% female and 90% diagnosed by sputum. Clinical symptoms included severe cough (90%), sputum production (70%), haemoptysis (50%), and chest pain (35%). Comorbidities included a history of tuberculosis (60%), smoking (40%), or chronic obstructive pulmonary disease (20%). Patients were treated with levofloxacin, clarithromycin, and co-trimoxazole. Except for two patients, the clinical symptoms improved. pulmonary infection is increasing in people with underlying diseases. Although choosing the most appropriate treatment remains a challenge, combining successful treatments could be useful in treating these patients.
肺部感染的发病率正在上升，其诊断和治疗具有挑战性。我们调查了伊朗东北部20例经线性探针分析诊断并通过对（）区域测序确认的患者的临床特征、危险因素、诊断和管理情况，并使用关键词“肺部感染”和“.”进行了文献综述。患者的平均年龄为55.1岁，80%为女性，90%通过痰液诊断。临床症状包括剧烈咳嗽（90%）、咳痰（70%）、咯血（50%）和胸痛（35%）。合并症包括有结核病病史（60%）、吸烟（40%）或慢性阻塞性肺疾病（20%）。患者接受了左氧氟沙星、克拉霉素和复方新诺明治疗。除两名患者外，临床症状均有改善。肺部感染在有基础疾病的人群中正在增加。尽管选择最合适的治疗方法仍然是一项挑战，但联合成功的治疗方法可能有助于治疗这些患者。
