Frecska E, Lukács H, Arató M, Mód L, Alföldi A, Magyar I
National Institute of Nervous and Mental Diseases, Budapest, Hungary.
Psychiatry Res. 1988 Feb;23(2):137-45. doi: 10.1016/0165-1781(88)90003-0.
The dexamethasone suppression test (DST) and the Minnesota Multiphasic Personality Inventory (MMPI) were administered to 144 healthy inductees on day 2 of military service. One hundred and four of them completed a 120-item questionnaire describing their coping responses to this particular challenge. Thirty-six subjects (25%) failed to suppress plasma cortisol adequately. Their mean scores on the MMPI clinical standard scales were within the normal range. High postdexamethasone cortisol levels were associated with denial and passivity, and with low demand for social support. These results suggest that the DST might be more related to coping with a stressor than to a specific diagnosis. The authors speculate that high hypothalamic-pituitary-adrenal activity may have a primary role in psychological defense promoting inattention to the aversive aspects of stressful situations.
在新兵入伍第2天，对144名健康新兵进行了地塞米松抑制试验（DST）和明尼苏达多相人格调查表（MMPI）测试。其中104人完成了一份120项的问卷，描述了他们应对这一特殊挑战的应对反应。36名受试者（25%）未能充分抑制血浆皮质醇。他们在MMPI临床标准量表上的平均得分在正常范围内。地塞米松给药后皮质醇水平高与否认和被动以及对社会支持的低需求有关。这些结果表明，DST可能更多地与应对压力源有关，而非与特定诊断有关。作者推测，下丘脑 - 垂体 - 肾上腺活动增强可能在促进对压力情境厌恶方面注意力不集中的心理防御中起主要作用。
