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历史视角:梅契尼科夫与肠道微生物组。

Historical Perspective: Metchnikoff and the intestinal microbiome.

机构信息

Centre for Immunobiology, Institute of Infection, Immunology and Inflammation, Sir Graeme Davies Building, University of Glasgow, Glasgow, UK.

出版信息

J Leukoc Biol. 2021 Mar;109(3):513-517. doi: 10.1002/JLB.4RI0920-599.

DOI:10.1002/JLB.4RI0920-599
PMID:33630385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10016786/
Abstract

Metchnikoff's essay, Intestinal Bacteriotherapy, was written when the study of microbiology was still in its infancy and few intestinal diseases had been ascribed to a specific bacterial infection. Metchnikoff offered perceptive ideas that have become standard in today's science. This Historical Perspectives commentary examines how Metchnikoff's article influenced our field. An accompanying editorial by Siamon Gordon explores this topic further and describes the relevance of Metchnikoff's work to the current Covid-19 infection. We also include a translation of this fundamental article by Metchnikoff, as presented by Claudine Neyen.

摘要

梅契尼科夫的论文《肠道细菌疗法》写于微生物学研究仍处于起步阶段、很少有肠道疾病被归因于特定细菌感染的时候。梅契尼科夫提出了一些有洞察力的观点,这些观点在今天的科学中已经成为标准。这篇历史透视评论探讨了梅契尼科夫的文章如何影响我们的领域。西阿莫恩·戈登(Siamon Gordon)的一篇评论文章进一步探讨了这一主题,并描述了梅契尼科夫的工作与当前新冠病毒感染的相关性。我们还包括克劳丁·奈延(Claudine Neyen)翻译的梅契尼科夫这篇重要文章。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9a6/10016786/1ca872d78e8c/jlb10864-gra-0001-m.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9a6/10016786/1ca872d78e8c/jlb10864-gra-0001-m.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9a6/10016786/1ca872d78e8c/jlb10864-gra-0001-m.jpg

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Cell Host Microbe. 2020 Aug 12;28(2):180-189. doi: 10.1016/j.chom.2020.07.013.
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Uncovering the role of the gut microbiota in immune checkpoint blockade therapy: A mini-review.揭示肠道微生物群在免疫检查点阻断治疗中的作用:一篇综述。
Semin Hematol. 2020 Jan;57(1):13-18. doi: 10.1053/j.seminhematol.2020.05.002. Epub 2020 May 19.
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From Association to Causality: the Role of the Gut Microbiota and Its Functional Products on Host Metabolism.从关联到因果关系:肠道微生物群及其功能产物对宿主代谢的作用。
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