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[胸腺细胞和外周血淋巴细胞辐射后凋亡死亡的电子显微镜分析]

[Electron microscopic analysis of postradiation apoptotic death of thymocytes and peripheral blood lymphocytes].

作者信息

Koliubaeva S N, Stepanov R P, Shchedrina L V, Zvonareva N B, Komar V E

出版信息

Radiobiologiia. 1988 Mar-Apr;28(2):189-94.

PMID:3363095
Abstract

Some stages of the apoptotic death of lymphoid cells (thymocytes and peripheral blood lymphocytes) have been followed up using light and electron microscopes. Differences have been revealed in the formation of death stages under natural physiological conditions and after gamma-irradiation. High radiation doses are shown to interfere with the process of nuclear chromatin condensation characteristic of the natural physiological death of cells.

摘要

利用光学显微镜和电子显微镜对淋巴样细胞(胸腺细胞和外周血淋巴细胞)凋亡死亡的某些阶段进行了追踪。已揭示出在自然生理条件下和γ射线照射后细胞死亡阶段形成过程中的差异。高辐射剂量显示会干扰细胞自然生理死亡所特有的核染色质凝聚过程。

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