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Elevated expression of lung development-related protein HSP90β indicates poor prognosis in non-small cell lung cancer through affecting the cell cycle and apoptosis.

作者信息

Wang Xiang, Wang Yaru, Feng Lin, Wang Minghui, Zhang Kaitai, Mao Yousheng, Xiao Ting, Cheng Shujun

机构信息

State Key Laboratory of Molecular Oncology, Department of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

出版信息

Signal Transduct Target Ther. 2021 Feb 26;6(1):82. doi: 10.1038/s41392-021-00465-y.

DOI:10.1038/s41392-021-00465-y
PMID:33633110
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7907212/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d823/7907212/772368f399df/41392_2021_465_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d823/7907212/772368f399df/41392_2021_465_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d823/7907212/772368f399df/41392_2021_465_Fig1_HTML.jpg

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本文引用的文献

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Integrative Proteomic Characterization of Human Lung Adenocarcinoma.人类肺腺癌的综合蛋白质组学特征分析。
Cell. 2020 Jul 9;182(1):245-261.e17. doi: 10.1016/j.cell.2020.05.043.
2
Crosstalk of dynamic functional modules in lung development of rhesus macaques.恒河猴肺发育中动态功能模块的相互作用
Mol Biosyst. 2016 Apr;12(4):1342-9. doi: 10.1039/c5mb00881f. Epub 2016 Feb 29.
3
Gene expression profiling in human lung development: an abundant resource for lung adenocarcinoma prognosis.人类肺发育过程中的基因表达谱分析：肺癌腺癌预后的丰富资源。
四蛋白模型预测肺癌预后风险。
Front Med. 2022 Aug;16(4):618-626. doi: 10.1007/s11684-021-0867-0. Epub 2022 Mar 9.
PLoS One. 2014 Aug 20;9(8):e105639. doi: 10.1371/journal.pone.0105639. eCollection 2014.
4
Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients.Hsp90-beta 和膜联蛋白 A1 的上调与肺癌患者的不良生存和淋巴转移相关。
J Exp Clin Cancer Res. 2012 Aug 28;31(1):70. doi: 10.1186/1756-9966-31-70.
5
The relationship between early embryo development and tumourigenesis.早期胚胎发育与肿瘤发生的关系。
J Cell Mol Med. 2010 Dec;14(12):2697-701. doi: 10.1111/j.1582-4934.2010.01191.x.