Chihaya Y, Matsukawa K, Mizushima S, Matsui Y
Department of Veterinary Pathology, School of Veterinary Medicine, College of Dairying, Hokkaido, Japan.
Vet Pathol. 1988 Mar;25(2):119-23. doi: 10.1177/030098588802500203.
Spores of Absidia corymbifera were inoculated orally into sheep with ruminal acidosis produced by feeding barley. Lesions, which developed in forestomachs of all four inoculated cases, included desquamation of superficial layers of the mucosae and focal necrosis from lamina propria to muscular layers. Granulomatous lesions were in the submucosa of three sheep. Lesions in the abomasum (two sheep) included focal necrosis, diffuse hemorrhages, and infiltration of neutrophils. All lesions were accompanied by mycotic proliferation. These results show that A. corymbifera can invade forestomach mucosae through degenerate epithelium resulting from ruminal acidosis.
将伞枝犁头霉的孢子经口接种到因喂食大麦而患瘤胃酸中毒的绵羊体内。在所有4例接种病例的前胃中出现的病变包括黏膜表层的脱落以及从固有层到肌层的局灶性坏死。3只绵羊的黏膜下层出现肉芽肿性病变。2只绵羊的皱胃病变包括局灶性坏死、弥漫性出血和中性粒细胞浸润。所有病变均伴有真菌增殖。这些结果表明，伞枝犁头霉可通过瘤胃酸中毒导致的上皮变性侵入前胃黏膜。
