Department of Anesthesiology and Reanimation, Bursa Yuksek Ihtisas Training and Research Hospital, University of Health Sciences, Mimar Sinan Mah. Emniyet Street Yıldırım, Bursa, Turkey.
J Med Ultrason (2001). 2021 Apr;48(2):245-252. doi: 10.1007/s10396-021-01081-7. Epub 2021 Feb 26.
The purpose of our study was to determine the usability of lung ultrasonography (LUS) in the diagnosis of COVID-19, and to match the morphological features of lesions detected on computed tomography (CT) with the findings observed on LUS.
Sixty patients with COVID-19 were included in this prospective study. Patients were examined by radiology and anesthesia clinic specialists for a visual CT score. A LUS 12-zone ultrasonography protocol was applied by the investigator blinded to the CT and PCR test results. The characteristics of abnormal findings and the relationship of lesions to the pleura and the distance to the pleura were investigated.
Forty-five males and 25 females evaluated within the scope of the study had an average age of 61.2 ± 15.3 years. The total CT score was calculated as 14.3 ± 5.3, and the LUS score was found to be 19.9 ± 7.6. There was a statistically significant positive correlation between the measured LUS and CT scores (r = 0.857, p < 0.001). The mean distance of these lesions to the pleura was 5.2 ± 1.76 cm. LUS findings in 51 areas corresponded to non-pleural lesions on CT. There was a negative correlation between the measured distance to the pleura and the LUS scores (p < 0.001, r = - 0.708).
The results of this study showed that the correlation between CT and LUS findings may be used in the diagnosis of COVID-19 pneumonia, although there are some limitations. ClinicalTrials.gov identifier: NCT04719234.
本研究旨在确定肺部超声(LUS)在 COVID-19 诊断中的可用性,并将 CT 检测到的病变形态特征与 LUS 观察到的结果相匹配。
本前瞻性研究纳入了 60 例 COVID-19 患者。患者由放射科和麻醉科专家进行视觉 CT 评分检查。研究者对 LUS 12 区超声协议进行了评估,该协议对 CT 和 PCR 检测结果是盲法的。研究调查了异常发现的特征以及病变与胸膜的关系和与胸膜的距离。
在研究范围内评估的 45 名男性和 25 名女性的平均年龄为 61.2±15.3 岁。总 CT 评分为 14.3±5.3,LUS 评分为 19.9±7.6。测量的 LUS 和 CT 评分之间存在显著的正相关(r=0.857,p<0.001)。这些病变与胸膜的平均距离为 5.2±1.76cm。CT 上 51 个区域的 LUS 发现与非胸膜病变相对应。测量的距离与 LUS 评分之间存在负相关(p<0.001,r=-0.708)。
本研究结果表明,CT 和 LUS 检查结果之间的相关性可用于 COVID-19 肺炎的诊断,尽管存在一些局限性。临床试验.gov 标识符:NCT04719234。