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Berberine reduces circulating inflammatory mediators in patients with severe COVID-19.

作者信息

Zhang B Y, Chen M, Chen X C, Cao K, You Y, Qian Y J, Yu W K

机构信息

Department of Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, No. 321 Zhongshan Road, Nanjing, Jiangsu Province 210008, China.

出版信息

Br J Surg. 2021 Jan 27;108(1):e9-e11. doi: 10.1093/bjs/znaa021.

DOI:10.1093/bjs/znaa021
PMID:33640910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7799351/
Abstract
摘要

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本文引用的文献

1
Direct endothelial damage and vasculitis due to SARS-CoV-2 in small bowel submucosa of COVID-19 patient with diarrhea.新型冠状病毒肺炎腹泻患者小肠黏膜下层因严重急性呼吸综合征冠状病毒2导致的直接内皮损伤和血管炎
J Med Virol. 2021 Jan;93(1):61-63. doi: 10.1002/jmv.26119. Epub 2020 Jun 24.
2
Faecal calprotectin indicates intestinal inflammation in COVID-19.粪便钙卫蛋白提示新冠病毒感染患者存在肠道炎症。
Gut. 2020 Aug;69(8):1543-1544. doi: 10.1136/gutjnl-2020-321388. Epub 2020 Apr 20.
3
Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS.小檗碱通过诱导线粒体自噬和减少线粒体 ROS 来抑制流感病毒触发的巨噬细胞中的 NLRP3 炎性体激活。
J Leukoc Biol. 2020 Jul;108(1):253-266. doi: 10.1002/JLB.3MA0320-358RR. Epub 2020 Apr 9.
4
Clinical characteristics of 25 death cases with COVID-19: A retrospective review of medical records in a single medical center, Wuhan, China.25 例 COVID-19 死亡病例的临床特征：对中国武汉某单一医疗中心病历的回顾性研究。
Int J Infect Dis. 2020 May;94:128-132. doi: 10.1016/j.ijid.2020.03.053. Epub 2020 Apr 3.
5
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.中国武汉成人 COVID-19 住院患者的临床病程和死亡危险因素：一项回顾性队列研究。
Lancet. 2020 Mar 28;395(10229):1054-1062. doi: 10.1016/S0140-6736(20)30566-3. Epub 2020 Mar 11.
6
Berberine improves intestinal epithelial tight junctions by upregulating A20 expression in IBS-D mice.小檗碱通过上调 IBS-D 小鼠 A20 的表达改善肠道上皮细胞紧密连接。
Biomed Pharmacother. 2019 Oct;118:109206. doi: 10.1016/j.biopha.2019.109206. Epub 2019 Jul 12.
7
In vivo and in vitro antiviral effects of berberine on influenza virus.小檗碱抗流感病毒的体内和体外抗病毒作用。
Chin J Integr Med. 2011 Jun;17(6):444-52. doi: 10.1007/s11655-011-0640-3. Epub 2011 Jun 10.