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Therapeutic potential of trehalose in neurodegenerative diseases: the knowns and unknowns.

作者信息

Khalifeh Masoomeh, Barreto George E, Sahebkar Amirhossein

机构信息

Department of Medical Biotechnology and Nanotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Biological Sciences; Health Research Institute, University of Limerick, Limerick, Ireland.

出版信息

Neural Regen Res. 2021 Oct;16(10):2026-2027. doi: 10.4103/1673-5374.308085.

DOI:10.4103/1673-5374.308085
PMID:33642389
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8343311/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f51/8343311/05706ac03f10/NRR-16-2026-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f51/8343311/05706ac03f10/NRR-16-2026-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f51/8343311/05706ac03f10/NRR-16-2026-g001.jpg

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Trehalose in Machado-Joseph Disease: Safety, Tolerability, and Efficacy.马查多-约瑟夫病中的海藻糖:安全性、耐受性和疗效。
Cerebellum. 2020 Oct;19(5):672-679. doi: 10.1007/s12311-020-01150-6.
3
Trehalase localization in the cerebral cortex, hippocampus and cerebellum of mouse brains.海藻糖酶在小鼠大脑皮层、海马体和小脑中的定位。
长链非编码RNA ABHD11-AS1通过吸附miR-876-5p上调钙调蛋白2以促进甲状腺癌转移。
Biochem Genet. 2025 Mar 21. doi: 10.1007/s10528-025-11072-9.
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Oral trehalose improves histological and behavior symptoms of mucopolysaccharidosis type II in iduronate 2-sulfatase deficient mice.口服海藻糖可改善艾杜糖醛酸2-硫酸酯酶缺陷小鼠的II型黏多糖贮积症的组织学和行为症状。
Sci Rep. 2025 Feb 10;15(1):4882. doi: 10.1038/s41598-025-88362-0.
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Biomedicines. 2024 Dec 26;13(1):29. doi: 10.3390/biomedicines13010029.
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Autophagy modulators in type 2 diabetes: A new perspective.2型糖尿病中的自噬调节剂:新视角
J Diabetes. 2024 Dec;16(12):e70010. doi: 10.1111/1753-0407.70010.
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Effect of oral trehalose supplementation on inflammation and wound healing in patients with peri-trochanteric fractures: study protocol for a randomised clinical trial.口服海藻糖补充剂对转子周围骨折患者炎症和伤口愈合的影响:一项随机临床试验的研究方案
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