McCarron Mark O, Clarke Mike, Burns Paul, McCormick Michael, McCarron Peter, Forbes Raeburn B, McCarron Luke V, Mullan Fiona, McVerry Ferghal
Department of Neurology, Altnagelvin Hospital, Derry, Ireland.
HSC Statistical and Methodological Support Service, Queen's University Belfast, Belfast, Ireland.
Front Neurol. 2021 Feb 12;12:608070. doi: 10.3389/fneur.2021.608070. eCollection 2021.
Nationwide disparities in managing neurological patients have rarely been reported. We compared neurological health care between the population who reside in a Health and Social Care Trust with a tertiary neuroscience center and those living in the four non-tertiary center Trusts in Northern Ireland. Using the tertiary center Trust population as reference, neurodisparity indices (NDIs) defined as the number of treated patients resident in each Trust per 100,000 residents compared to the same ratio in the tertiary center Trust for a fixed time period. NDIs were calculated for four neurological pathways-intravenous thrombolysis (iv-tPA) and mechanical thrombectomy (MT) for acute ischemic stroke (AIS), disease modifying treatment (DMT) in multiple sclerosis (MS) and admissions to a tertiary neurology ward. Neurological management was recorded in 3,026 patients. Patients resident in the tertiary center Trust were more likely to receive AIS treatments (iv-tPA and MT) and access to the neurology ward ( < 0.001) than patients residing in other Trusts. DMT use for patients with MS was higher in two non-tertiary center Trusts than in the tertiary center Trust. There was a geographical gradient for MT for AIS patients and ward admissions. Averaged NDIs for non-tertiary center Trusts were: 0.48 (95%CI 0.32-0.71) for patient admissions to the tertiary neurology ward, 0.50 (95%CI 0.38-0.66) for MT in AIS patients, 0.78 (95%CI 0.67-0.92) for iv-tPA in AIS patients, and 1.11 (95%CI 0.99-1.26) for DMT use in MS patients. There are important neurodisparities in Northern Ireland, particularly for MT and tertiary ward admissions. Neurologists and health service planners should be aware that geography and time-dependent management of neurological patients worsen neurodisparities.
全国范围内在神经科患者管理方面的差异鲜有报道。我们比较了居住在设有三级神经科学中心的健康与社会关怀信托机构的人群与居住在北爱尔兰四个非三级中心信托机构的人群在神经科医疗保健方面的情况。以三级中心信托机构的人群为参照,神经差异指数(NDIs)定义为在固定时间段内,每个信托机构每10万居民中接受治疗的患者数量与三级中心信托机构的相同比例相比。计算了四条神经科治疗途径的NDIs,即急性缺血性卒中(AIS)的静脉溶栓(iv-tPA)和机械取栓(MT)、多发性硬化症(MS)的疾病修正治疗(DMT)以及三级神经科病房的入院情况。记录了3026例患者的神经科治疗情况。与居住在其他信托机构的患者相比,居住在三级中心信托机构的患者更有可能接受AIS治疗(iv-tPA和MT)并进入神经科病房(<0.001)。两个非三级中心信托机构中MS患者的DMT使用率高于三级中心信托机构。AIS患者的MT和病房入院存在地理梯度。非三级中心信托机构的平均NDIs为:三级神经科病房患者入院为0.48(95%CI 0.32 - 0.71),AIS患者的MT为0.50(95%CI 0.38 - 0.66),AIS患者的iv-tPA为0.78(95%CI 0.67 - 0.92),MS患者的DMT使用为1.11(95%CI 0.99 - 1.26)。北爱尔兰存在重要的神经差异,特别是在MT和三级病房入院方面。神经科医生和卫生服务规划者应意识到,神经科患者的地理位置和时间依赖性管理会加剧神经差异。