Oleszkiewicz A, Schriever V A, Croy I, Hähner A, Hummel Thomas
Department of Otorhinolaryngology, Smell and Taste Clinic, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Institute of Psychology, University of Wroclaw, ul. Dawida 1, 50527, Wrocław, Poland.
Eur Arch Otorhinolaryngol. 2019 Mar;276(3):719-728. doi: 10.1007/s00405-018-5248-1. Epub 2018 Dec 15.
To provide up-to-date and detailed normative data based on a large-scale sample, increasing diagnostic validity by reference to narrow age groups as previous normative values were based upon smaller sample sizes-especially in the group of older subjects.
Data were obtained from 9139 healthy subjects (4928 females aged 5-96 years and 4211 males aged 5-91 years). The standard "Sniffin' Sticks" test was applied, comprising threshold (T), discrimination (D) and identification (I) subtests, and yielding a TDI sum score.
Hyposmia was established at a TDI score of less than 30.75. Age-related changes were found in each domain, most pronounced for thresholds. Individuals aged 20-30 years performed best, whereas children below the age of 10 and adults above the age of 71 scored only half as well. Sex-related differences were in favor of women.
Data provide guidance for assessing individual olfactory performance in relation to specific age groups. Significant gender and age effects were observed, with a most pronounced increase of olfactory test scores between age 5 through 20 years and a dramatic decrease at the age of 60 through 71 years.
基于大规模样本提供最新且详细的规范数据,通过参照更窄的年龄组来提高诊断效度,因为之前的规范值是基于较小样本量得出的,尤其是在老年受试者组中。
数据来自9139名健康受试者(4928名年龄在5至96岁的女性和4211名年龄在5至91岁的男性)。应用标准的“嗅觉棒”测试,包括阈值(T)、辨别力(D)和识别(I)子测试,并得出TDI总分。
TDI得分低于30.75被判定为嗅觉减退。在每个领域都发现了与年龄相关的变化,阈值方面最为明显。20至30岁的个体表现最佳,而10岁以下儿童和71岁以上成年人的得分仅为前者的一半。与性别相关的差异有利于女性。
这些数据为评估特定年龄组个体的嗅觉表现提供了指导。观察到显著的性别和年龄效应,嗅觉测试分数在5至20岁之间增长最为显著,在60至71岁时急剧下降。