Mak Hugo W F, Ho Shi Yeung, Wong Jane C Y, Chiang Valerie, Lee Elaine, Yim Jackie S H, Wong Birgitta Y H, Li Philip H
Division of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Department of Ear, Nose and Throat, Queen Mary Hospital, Hong Kong, Hong Kong SAR, China.
Front Allergy. 2024 Jan 24;5:1292342. doi: 10.3389/falgy.2024.1292342. eCollection 2024.
Olfactory dysfunction (OD) is common among patients with chronic rhinosinusitis (CRS). Validated and culturally specific tests, such as the "Sniffin' Sticks" test (SST) and the TIB Smell Identification Test (TIBSIT), are crucial for the diagnosis and monitoring of OD. However, they have not been utilised in Hong Kong Chinese and their correlations are unknown.
Twelve CRS patients and twenty healthy volunteers were prospectively recruited from a joint allergy-otorhinolaryngology clinic in Hong Kong and performed both SST and TIBSIT. Demographics, baseline characteristics and all test results were compared and analysed.
Patients with CRS demonstrated significantly lower test scores than healthy controls (all < 0.001). Significant and strong correlations were observed between all composite and subtest scores, particularly between the composite SST and TIBSIT scores ( = 0.789, < 0.001). Multivariate analysis demonstrated that the presence of CRS and increasing age were significantly associated with OD.
Both SST and TIBSIT are useful olfactory tests and are strongly correlated among Hong Kong Chinese. We advocate that either test can be used for measuring OD among CRS patients.
嗅觉功能障碍(OD)在慢性鼻-鼻窦炎(CRS)患者中很常见。经过验证且具有文化特异性的测试,如“嗅觉棒”测试(SST)和TIB嗅觉识别测试(TIBSIT),对于OD的诊断和监测至关重要。然而,它们尚未在香港华人中使用,其相关性也未知。
前瞻性地从香港一家联合过敏-耳鼻喉科诊所招募了12名CRS患者和20名健康志愿者,并进行了SST和TIBSIT测试。比较并分析了人口统计学、基线特征和所有测试结果。
CRS患者的测试分数显著低于健康对照组(所有P<0.001)。在所有综合和子测试分数之间观察到显著且强烈的相关性,特别是在SST综合分数和TIBSIT分数之间(r=0.789,P<0.001)。多变量分析表明,CRS的存在和年龄增长与OD显著相关。
SST和TIBSIT都是有用的嗅觉测试,并且在香港华人中具有很强的相关性。我们主张这两种测试均可用于测量CRS患者的OD。