University of South Wales, Pontypridd, Wales, United Kingdom; The Student Science and Technology Online Research Coop, Ontario, Canada.
Pharmaceutical division, ministry of health and population, Cairo, Egypt.
J Infect Public Health. 2021 Mar;14(3):389-416. doi: 10.1016/j.jiph.2020.12.025. Epub 2020 Dec 30.
Severe acute respiratory syndrome coronavirus (SARS-CoV-2), a novel corona virus, causing COVID-19 with Flu-like symptoms is the first alarming pandemic of the third millennium. SARS-CoV-2 belongs to beta coronavirus as Middle East respiratory syndrome coronavirus (MERS-CoV). Pandemic COVID-19 owes devastating mortality and destructively exceptional consequences on Socio-Economics life around the world. Therefore, the current review is redirected to the scientific community to owe comprehensive visualization about SARS-CoV-2 to tackle the current pandemic. As systematically shown through the current review, it indexes unmet medical problem of COVID-19 in view of public health and vaccination discovery for the infectious SARS-CoV-2; it is currently under-investigational therapeutic protocols, and next possible vaccines. Furthermore, the review extensively reports the precautionary measures to achieve" COVID-19/Flatten the curve". It is concluded that vaccines formulation within exceptional no time in this pandemic is highly recommended, via following the same protocols of previous pandemics; MERS-CoV and SARS-CoV, and excluding some initial steps of vaccination development process.
严重急性呼吸系统综合症冠状病毒（SARS-CoV-2），一种新型冠状病毒，引起类似流感的症状的 COVID-19，是第三个千年的第一次警戒性大流行。SARS-CoV-2 属于贝塔冠状病毒，就像中东呼吸系统综合症冠状病毒（MERS-CoV）一样。大流行的 COVID-19 在全球范围内对社会经济生活造成了毁灭性的高死亡率和异常后果。因此，目前的综述是针对科学界的，旨在全面了解 SARS-CoV-2，以应对当前的大流行。正如本综述系统地显示的那样，它指出了 COVID-19 在公共卫生和传染病 SARS-CoV-2 疫苗发现方面存在未满足的医疗问题；目前正在研究治疗方案，以及未来可能的疫苗。此外，该综述还广泛报道了实现“COVID-19/平缓曲线”的预防措施。结论是，强烈建议在大流行期间，通过遵循之前大流行（MERS-CoV 和 SARS-CoV）的相同方案，并省略疫苗开发过程的一些初始步骤，在极短时间内制定疫苗配方。
