Shaik Riyaz Ahamed, Ahmad Mohammed Shakil, Alzahrani Mansour, Alzerwi Nasser A N, Alnemare Ahmad K, Reyzah Musaed, Albar Haitham M, Alshagrawi Salah, Elkhalifa Ahmed M E, Alzahrani Raed, Alrohaimi Yousef, Mahfoz Turki M Bin, Ahmad Ritu Kumar, Alahmdi Riyadh Ahmed, Al-Baradie Nora Raid Saleem
Department of Family and Community Medicine, College of Medicine, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Department of Surgery, College of Medicine, Majmaah University, Ministry of Education, Al Majmaah 11952, Saudi Arabia.
Vaccines (Basel). 2022 Oct 10;10(10):1689. doi: 10.3390/vaccines10101689.
The world has taken proactive measures to combat the pandemic since the coronavirus disease 2019 (COVID-19) outbreak, which was caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). These measures range from increasing the production of personal protective equipment (PPE) and highlighting the value of social distancing to the emergency use authorization (EUA) of therapeutic drugs or antibodies and their appropriate use; nonetheless, the disease is still spreading quickly and is ruining people's social lives, the economy, and public health. As a result, effective vaccines are critical for bringing the pandemic to an end and restoring normalcy in society. Several potential COVID-19 vaccines are now being researched, developed, tested, and reviewed. Since the end of June 2022, several vaccines have been provisionally approved, whereas others are about to be approved. In the upcoming years, a large number of new medications that are presently undergoing clinical testing are anticipated to hit the market. To illustrate the advantages and disadvantages of their technique, to emphasize the additives and delivery methods used in their creation, and to project potential future growth, this study explores these vaccines and the related research endeavors, including conventional and prospective approaches.
自2019年冠状病毒病（COVID-19）爆发以来，全球已采取积极措施抗击这一由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的大流行病。这些措施包括增加个人防护装备（PPE）的生产、强调社交距离的重要性，以及治疗药物或抗体的紧急使用授权（EUA）及其合理使用；尽管如此，该疾病仍在迅速传播，破坏着人们的社会生活、经济和公共卫生。因此，有效的疫苗对于结束大流行和恢复社会正常状态至关重要。目前有几种潜在的COVID-19疫苗正在进行研究、开发、测试和审评。自2022年6月底以来，已有几种疫苗获得临时批准，而其他疫苗也即将获批。在未来几年，预计大量目前正在进行临床试验的新药物将投放市场。为了说明其技术的优缺点，强调其生产中使用的添加剂和递送方法，并预测未来的潜在增长，本研究探讨了这些疫苗及相关研究工作，包括传统方法和前瞻性方法。
