Grupo de Fisiopatología de la Reproducción, Departamento Producción y Sanidad Animal, Salud Pública y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain.
Res Vet Sci. 2021 May;136:166-173. doi: 10.1016/j.rvsc.2021.02.016. Epub 2021 Feb 22.
Embryo implantation is a complex process in which significant changes occur continually in both the corpora lutea and in the endometrium of females and which varies depending on the embryonic, pre-implantation, or fetal stages. However, at all stages, correct maternal-embryonic communication is essential. In the last few years, a new intercellular communication tool, mediated by extracellular vesicles (EVs), has emerged. Many authors agree on the relevant role of EVs in correct communication between the mother and the embryo, as a fundamental system for the pregnancy to reach term and embryonic development to occur correctly. This review analyzes current information on known EVs, their main functions, and their role in implantation and embryonic development in domestic animals.
胚胎着床是一个复杂的过程，在此过程中，女性的黄体和子宫内膜会不断发生显著变化，并且这种变化因胚胎、着床前或胎儿阶段而异。然而，在所有阶段，正确的母婴交流都是至关重要的。在过去的几年中，一种新的细胞间通讯工具，即细胞外囊泡（EVs），已经出现。许多作者都认为 EVs 在母胎之间的正确通讯中具有重要作用，是妊娠足月和胚胎发育正常进行的基本系统。这篇综述分析了目前关于家畜中已知的 EVs、它们的主要功能及其在着床和胚胎发育中的作用的信息。
