Department of General Surgery, MedStar Georgetown University Hospital, Washington, DC, USA.
Department of Plastic Surgery, UT Southwestern Medical Center, Dallas, TX, USA.
Aesthet Surg J. 2021 Sep 14;41(10):1155-1165. doi: 10.1093/asj/sjaa418.
Despite the proven efficacy of liposuction, there is a population of patients who prefer non-surgical alternatives. Laser hyperthermia-induced lipolysis has emerged as one non-invasive alternative to liposuction.
The authors sought to evaluate the safety and efficacy of a 1060-nm (±10 nm) diode laser for non-invasive fat reduction of the abdomen.
This single-arm, 2-center study enrolled 30 patients. Patients received a 25-minute 1060-nm diode laser treatment on their abdomen. Ultrasound adipose measurements, body weight, and circumference were taken at baseline and at 6- and 12-week follow-up visits. Blinded evaluators identified "before" and "after" photos of each patient. A patient satisfaction questionnaire was completed by each patient at study exit.
A total 29 patients completed all treatment and follow-up visits. Ultrasound images showed an adipose reduction of 8.55% at 12 weeks post-treatment (P < 0.0001). Blinded evaluators correctly identified 67% of the pre- and post-treatment images at site 01 (Sacramento, CA) and 56% at site 02 (Dallas, TX). Satisfaction was high, with 72% of patients reporting being either "satisfied" or "very satisfied" with their results on a 5-point Likert scale. Pain was rated as mild by 62% of patients, moderate by 38%, and severe by none on the Wong-Baker Scale.
These results indicate that a single treatment with a 1060-nm (±10 nm) diode laser, per the treatment protocol, is safe and effective in reducing unwanted fat in the abdomen as objectively measured employing ultrasound. The treatment was well-tolerated among all patients, with minimal discomfort reported and high patient satisfaction.
尽管吸脂术已被证实有效，但仍有一部分患者更喜欢非手术替代方法。激光热疗诱导的脂肪分解已成为吸脂术的一种非侵入性替代方法。
作者旨在评估 1060nm（±10nm）二极管激光用于腹部无创性脂肪减少的安全性和有效性。
这是一项单臂、2 中心研究，共纳入 30 例患者。患者接受 25 分钟 1060nm 二极管激光腹部治疗。在基线和 6 周及 12 周随访时测量超声脂肪测量值、体重和腰围。盲法评估者识别每位患者的“治疗前”和“治疗后”照片。每位患者在研究结束时完成一份患者满意度问卷。
共有 29 例患者完成了所有治疗和随访。超声图像显示治疗后 12 周脂肪减少 8.55%（P<0.0001）。盲法评估者在站点 01（加利福尼亚州萨克拉门托）正确识别了 67%的治疗前和治疗后图像，在站点 02（德克萨斯州达拉斯）正确识别了 56%的图像。患者满意度很高，72%的患者在 5 分制 Likert 量表上报告对治疗结果“满意”或“非常满意”。62%的患者将疼痛评为轻度，38%的患者评为中度，无人评为重度。
这些结果表明，按照治疗方案，单次使用 1060nm（±10nm）二极管激光治疗是安全有效的，可客观地使用超声测量减少腹部多余脂肪。所有患者均能耐受治疗，报告的不适感最小，患者满意度高。
